Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

Crossref logo

Fol. Biol. 2001, 47, 55-61

https://doi.org/10.14712/fb2001047020055

Production of TGF-β1 in Lungs after Low-Dose Whole-Body Radiation Exposure in Fibrosing (C57BL/6) and Non-fibrosing (C3H/J) Mouse Strain

Tomáš Olejár1,2, M. Zadinová1, D. Hloušková1, P. Poučková1

1Institute of Biophysics, 1st Medical Faculty, Charles University, Prague, Czech Republic
2Institute of Pathology, 1st Medical Faculty, Charles University, Prague, Czech Republic

Received June 2000
Accepted November 2000

References

1. Anscher, M. S., Kong, F. M., Andrews, K., Clough, R., Marks, L. B., Bentel, G., Jirtle, R. L. (1998) Plasma transforming growth factor betal as a predictor of radiation pneumonitis. Int. J. Radiat. Oncol. Biol. Phys. 41, 1029-1035. <https://doi.org/10.1016/S0360-3016(98)00154-0>
2. Franko, A. J., Sharplin, J., Ghahary, A., Barcellos-Hoff, M. H. (1997) Immunohistochemical localization of transforming lungs of fibrosis-prone and "non-fibrosing" mice during the latent period and early phase after irradiation. Radiat. Res. 147, 245-256. <https://doi.org/10.2307/3579426>
3. Grande, J. (1997) Role of transforming growth factor-β in tissue injury and repair. Proc. Soc. Exp. Biol. Med. 214, 27-40. <https://doi.org/10.3181/00379727-214-44066>
4. Grande, J., Melder, D., Zinsmeister, A., Killen, P. (1993) Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells. Lab. Invest. 69, 387-95.
5. Grande, J. P., Melder, D. C., Zinsmeister A. R., (1997) Modulation of collagen gene expression by cytokines: stimulatory effect of transforming growth factor-beta1, with divergent effects of epidermal growth factor and tumor necrosis factor-alpha on collagen type I and collagen type IV. J. Lab. Clin. Med. 130, 476-86. <https://doi.org/10.1016/S0022-2143(97)90124-4>
6. Guerry-Force, M. L., Perkett, E. A., Brigham, K. L., Meyrick, B. (1988) Early structural changes in sheep lung following thoracic irradiation. Radiat. Res. 114, 138-153. <https://doi.org/10.2307/3577151>
7. Haston, C. K., Travis, E. L. (1997) Murine susceptibility to radiation-induced pulmonary fibrosis is influenced by a genetic factor implicated in susceptibility to bleomycin-induced pulmonary fibrosis. Cancer Res. 57, 5286-5291.
8. Hauer-Jensen, M., Richter, K. K., Wang, J., Abe, E., Sung, C., Hardin, J. W. (1998) Changes in transforming growth factor beta1 gene expression and immunoreactivity levels during development of chronic radiation enteropathy. Radiat. Res. 150, 673-80. <https://doi.org/10.2307/3579890>
9. Herskind, C., Bamberg, M., Rodemann, H. P. (1998) The role of cytokines in the development of normal-tissue reactions after radiotherapy. Strahlenther. Onkol. 174, 12-15.
10. Johnston, C. J., Piedboeuf, B., Rubin, P., Williams, J. P., Baggs, R., Finkelstein, J. N. (1996) Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation. Radiat. Res. 145, 762-767. <https://doi.org/10.2307/3579368>
11. Li, C., Wilson, P. B., Levine, E., Barber, J., Stewart, A. L., Kumar, S. (1999) TGF-beta1 levels in pre-treatment plasma identify breast cancer patients at risk of developing post-radiotherapy fibrosis. Int. J. Cancer 20, 155-159.
12. Li, H., He, B., Que, C., Weng, B. (1996) Expression of TGF-beta 1, PDGF and IGF-1 mRNA in lung of bleomycin-A5-induced pulmonary fibrosis in rats. Chin. Med. J. (Engl.) 109, 533-536.
13. Nakayama, T., Nakamura, W. (1984) Platelet aggregation induced in mice by whole-body hyperthermia. Radiat. Res. 98, 583-590. <https://doi.org/10.2307/3576490>
14. Piguet, P. F., Vesin, C. (1994) Pulmonary platelet trapping induced by bleomycin: correlation with fibrosis and involvement of the beta 2 integrins. Int. J. Exp. Pathol. 75, 321-328.
15. Randall, K., Coggle, J. E. (1995) Expression of transforming growth factor-beta 1 in mouse skin during the acute phase of radiation damage. Int. J. Radiat. Biol. 68, 301-309. <https://doi.org/10.1080/09553009514551231>
16. Randall, K., Coggle, J. E. (1996) Long-term expression of transforming growth factor TGF beta 1 in mouse skin after localized beta-irradiation. Int. J. Radiat. Biol. 70, 351-60. <https://doi.org/10.1080/095530096145085>
17. Rubin, P., Johnston, C. J., Williams, J. P., McDonald, S., Finkelstein, J. N. (1995) A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 33, 99-109. <https://doi.org/10.1016/0360-3016(95)00095-G>
18. Sadilkova, M., Pospisil, J., Dienstbier, Z. (1981) Changes of thrombocytopoiesis during the first week after irradiation with doses of 2 Gy and 4 Gy. Sb. Lek. 83, 105-112.
19. Senaldi, G., Piguet, P. F. (1997) Platelets play a role in the pathogenesis of the irritant reaction in mice. J. Invest. Dermatol. 108, 248-252. <https://doi.org/10.1111/1523-1747.ep12286444>
20. Tacchini-Cottier, F., Vesin, C., Redard, M., Buurman, W., Piguet, P. F. (1998) Role of TNFR1 and TNFR2 in TNF-induced platelet consumption in mice. J. Immunol. 160, 6182-6186. <https://doi.org/10.4049/jimmunol.160.12.6182>
21. Thomas, C. (1989) Electron microscopy. In: Histopathology, ed. Thomas, C., pp. 14-20, B. C. Decker Inc., Toronto, Philadelphia.
22. Vujaskovic, Z., Down, J. D., van Waarde, M. A., van Assen, A. J., Szabo, B. G., Konings, A. W. (1997) Plasma TGF-β level in rats after hemithoracic irradiation. Radiother. Oncol. 44, 41-43. <https://doi.org/10.1016/S0167-8140(97)00075-3>
23. Wang, J., Zheng, H., Sung, C. C., Richter, K. K., Hauer-Jensen, M. (1998) Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy. Am. J. Pathol. 153, 1531-40. <https://doi.org/10.1016/S0002-9440(10)65741-0>
24. Ward, H. E., Kemsley, L., Davies, L., Holecek, M., Berend, A. (1993) The pulmonary response to sublethal thoracic irradiation in the rat. Radiat. Res. 136, 15-21. <https://doi.org/10.2307/3578634>
25. Waters, C. M., Taylor, J. M., Molteni, A., Ward, W. F. (1996) Dose-response effects of radiation on the permeability of endothelial cells in culture. Radiat. Res. 146, 321-328. <https://doi.org/10.2307/3579463>
26. Weir, G. J., Miachaelson, S. M. (1971) Microscopic pathology. In: Pulmonary Radiation Reactions, eds. Weir, G. J., Miachaelson, S. M., pp. 6-26, Charles C Thomas publisher, Springfield, Illinois.
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive