Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

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Fol. Biol. 2007, 53, 207-215

https://doi.org/10.14712/fb2007053060207

Downregulation of myc Promoter-Binding Protein 1 (MBP-1) in Growth-Arrested Malignant B cells

Daniel Tvrdík1, P. Dundr1, C. Povýšil1, P. Přikryl2, Š. Melčáková1, M. Planková1

1Institute of Pathology, Charles University in Prague, 1st Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic
2Institute of Pathological Physiology and Centre of Experimental Haematology, Charles University in Prague, 1st Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic

Received June 29, 2007
Accepted October 17, 2007

References

1. Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J. D. (1994) Molecular Biology of the Cell. 3rd edition, Garland Publishing, New York.
2. Alexandrow, M. G., Kawabata, M., Aakre, M., Moses, H. L. (1995) Overexpression of the c-Myc oncoprotein blocks the growth inhibitory response but is required for the mitogenic effects of transforming growth factor β1. Proc. Natl. Acad. Sci. USA 92, 3239-3243. <https://doi.org/10.1073/pnas.92.8.3239>
3. Amati, B., Brooks, M. W., Levy, N., Littlewood, T. D., Evan, G. I., Land, H. (1993) Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 72, 233-245. <https://doi.org/10.1016/0092-8674(93)90663-B>
4. Amin, C., Wagner, A. J., Hay, N. (1993) Sequence-specific transcriptional activation by Myc and repression by max. Mol. Cell Biol. 3, 383-390.
5. Arvanitakis, L., Yaseen, N., Sharma, S. (1995) Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-β 1-mediated growth inhibition in EBV-positive B cells. J. Immunol. 55, 1047-1056. <https://doi.org/10.4049/jimmunol.155.3.1047>
6. Aushubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K. (1992) Short Protocols in Molecular Biology. 2nd edition, John Wiley, New York.
7. Blackwell, T. K., Kretzner, L., Blackwood, E. M., Eisenman, R. N., Weintraub, H. (1990) Sequence specific DNA binding by the c-Myc protein. Science 250, 1149-1151. <https://doi.org/10.1126/science.2251503>
8. Blackwood, E. M., Eisenman, R. N. (1991) Max-A-helix-loop-helix zipper protein that forms a sequence-specific DNA binding complex with myc. Science 251, 1211-1217. <https://doi.org/10.1126/science.2006410>
9. Bouchard, C., Fridman, W. H., Cautes, C. (1997) Effects of TGF-β1 on cell cycle regulatory proteins in LPS-stimulated normal mouse B lymphocytes. J. Immunol. 159, 4155-4164. <https://doi.org/10.4049/jimmunol.159.9.4155>
10. Chaouchi, N., Arvanitakis, L., Auffredou, M. T., Blanchard, D. A., Vazquez, A., Sharma, S. (1995) Characterization of transforming growth factor-β 1 induced apoptosis in normal human B cells and lymphoma B cell lines. Oncogene 11, 1615-1622.
11. Chaudhary, D., Miller, D. M. (1995) The c-myc promoter binding protein (MBP-1) and TBP bind simultaneously in the minor groove of the c-myc P2 promoter. Biochemistry 34, 3438-3445. <https://doi.org/10.1021/bi00010a036>
12. Cole, M. (1986) The myc oncogene: its role in transformation and differentiation. Annu. Rev. Genet. 20, 361-384. <https://doi.org/10.1146/annurev.ge.20.120186.002045>
13. Dang, C. V., O'Donnell, K. A., Zeller, K. I., Nguyen, T., Osthus, R. C., Li, F. (2006) The c-Myc target gene network. Semin. Cancer Biol. 16, 253-264. <https://doi.org/10.1016/j.semcancer.2006.07.014>
14. Djaborkhel, R., Tvrdík, D., Eckschlager, T., Raška, I., Müller, J. (2000) Cyclin A down-regulation in TGFβ1-arrested follicular lymphoma. Exp. Cell Res. 261, 250-259. <https://doi.org/10.1006/excr.2000.5047>
15. Erikson, J., ar-Rushdi, A., Drwinga, H. L., Nowell, P. C., Croce, C. M. (1983) Transcriptional activation of the translocated c-myc oncogene in Burkitt lymphoma. Proc. Natl. Acad. Sci. USA 80, 820-824. <https://doi.org/10.1073/pnas.80.3.820>
16. Felsher, D. W, Zetterberg, A., Zhu, J., Tlsty, T., Bishop, J. M. (2000) Overexpression of MYC causes p53 dependent G2 arrest of normal fibroblasts. Proc. Natl. Acad. Sci. USA 97, 10544-10548. <https://doi.org/10.1073/pnas.190327097>
17. Feo, S., Arcuri, D., Piddini, E., Passantino, R., Giallongo, A. (2000) ENO1 gene product binds to the c-myc promoter and acts as a transcriptional repressor: relationship with Myc promoter-binding protein 1 (MBP-1). FEBS Lett. 473, 47-52. <https://doi.org/10.1016/S0014-5793(00)01494-0>
18. Gandarillas, A., Davies, D., Blanchard, J. M. (2000) Normal and c-Myc-promoted human keratinocyte differentiation both occur via a novel cell cycle involving cellular growth and endoreplication. Oncogene 19, 3278-3289. <https://doi.org/10.1038/sj.onc.1203630>
19. Giallongo, A., Feo, S., Moore, R., Croce, C. M., Showe, L. C. (1986) Molecular cloning and nucleotide sequence of a full-length cDNA for human α enolase. Proc. Natl. Acad. Sci. USA 83, 6741-6745. <https://doi.org/10.1073/pnas.83.18.6741>
20. Giallongo, A., Oliva, D., Cali, L., Barbra, G., Barbieri, G., Feo, S. (1990) Structure of the human gene for α-enolase. Eur. J. Biochem. 190, 567-573. <https://doi.org/10.1111/j.1432-1033.1990.tb15611.x>
21. Giallongo, A., Venturella, S., Oliva, D., Barbieri G., Rubino, P., Feo S. (1993) Structural features of the human gene for muscle-specific enolase. Differential splicing in the 5'-untranslated sequence generates two forms of mRNA. Eur. J. Biochem. 214, 367-374. <https://doi.org/10.1111/j.1432-1033.1993.tb17932.x>
22. Grau, A. M., Zhang, L., Wang, W., Ruan, S., Evans, D. B., Abbruzzese, J. L., Zhang, W., Chiao, P. J. (1997) Induction of p21waf1 expression and growth inhibition by transforming growth factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res. 57, 3929-3934.
23. Kim, J. W., Kim, H. S., Kim, I. K., Kim, M. R., Cho, E. Y., Kim, H. K., Lee, J. M., Namkoong, S. E. (1998) Transforming growth factor-β 1 induces apoptosis through down-regulation of c-myc gene and overexpression of p27Kip1 protein in cervical carcinoma. Gynecol. Oncol. 69, 230-236. <https://doi.org/10.1006/gyno.1998.5003>
24. Kluin-Nelemans, H. C., Limpers, J., Meerabux, J., Beverstock, G. C., Jansen, J. H., deJong, D., Kluin, P. M. (1991) A new non-Hodgkin's B-cell line DoHH2 with a chromosomal translocation t(14;18)(q32;q21). Leukemia 5, 221-224.
25. Ko, T. C., Sheng, H. M., Reisman, D., Thompson, E. A., Beauchamp, R. D. (1995) Transforming growth factor-β 1 inhibits cyclin D1 expression in intestinal epithelial cells. Oncogene 10, 177-184.
26. Lebioda, L., Stec, B. (1991) Mapping of isozymic differences in enolase. Int. J. Biol. Macromol. 13, 97-100. <https://doi.org/10.1016/0141-8130(91)90055-Y>
27. Malliri, A., Yeudall, W. A., Nikoli, M., Crouch, D. H., Parkinson, E. K. , Ozanne B. (1996) Sensitivity to transforming growth factor β 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-myc down-regulation and p21(waf1) induction are important early events. Cell Growth Differ. 7, 1291-1304.
28. Marcu, K. B., Bossone, S. A., Patel, A. J. (1992) Myc function and regulation. Annu. Rev. Biochem. 61, 809-860. <https://doi.org/10.1146/annurev.bi.61.070192.004113>
29. Munger, K., Pietenpol, J. A., Pittelkow, M. R., Holt, J. T., Moses, H. L. (1992) Transforming growth factor β 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes. Cell Growth Differ. 3, 291-298.
30. Oliva, D., Cali, L., Feo, S., Giallongo, A. (1991) Complete structure of the human gene encoding neuron-specific enolase. Genomics 10, 157-165. <https://doi.org/10.1016/0888-7543(91)90496-2>
31. Onyango, P., Lubyova, B., Gardellin, P., Kurzbauer, R., Weith, A. (1998) Molecular cloning and expression analysis of five novel genes in chromosome 1p36. Genomics 50, 187-198. <https://doi.org/10.1006/geno.1997.5186>
32. Pietenpol, A., Stein, R. W., Moran, E., Yaciuk, P., Schlegel, R., Lyons, R. M., Pittelkow, M. R., Munger, K., Howley, P. M., Moses, H. L. (1990) TGF-β 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell 61, 777-785. <https://doi.org/10.1016/0092-8674(90)90188-K>
33. Potter, M., Marcu, K. B. (1997) The c-myc story: where we've been, where we seem to be going. Curr. Top. Microbiol. Immunol. 224, 1-17.
34. Ray, R., Miller, D. M. (1991) Cloning and characterization of a human c-myc promoter-binding protein. Mol. Cell Biol. 11, 2154-2161.
35. Ray, R. B., Steele, R. (1997) Separate domains of MBP-1 involved in c-myc promoter binding and growth suppressive activity. Gene 186, 175-180. <https://doi.org/10.1016/S0378-1119(96)00693-2>
36. Ray, R., Thomas, S., Miller, O. M. (1989) Mouse fibroblasts transformed with the human c-myc gene express a high level of mRNA but a low level of c-myc protein and are non-tumorigenic in nude mice. Oncogene 4, 593-600.
37. Ray, R. B., Steele, R., Seftor, E., Hendrix, M. (1995) Human breast carcinoma cells transfected with the gene encoding c-myc promoter binding protein (MBP-I) shows tumor suppression in nude mice. Cancer Res. 55, 3747-3751.
38. Shipley, G. D., Tucker, R. F., Moses, H. L. (1985) Type β transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval. Proc. Natl. Acad. Sci. USA 82, 4147-4151. <https://doi.org/10.1073/pnas.82.12.4147>
39. Slingerland, J. M., Hengs, L., Pan, C. H., Alexander, D., Stampfer, M. R., Reed, S. I. (1994) A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells. Mol. Cell Biol. 14, 3683-3694.
40. Subramanian, A., Miller, D. M. (2000) Structural analysis of α-enolase. Mapping the functional domains involved in down-regulation of the c-myc protooncogene. J. Biol. Chem. 275, 5958-5965. <https://doi.org/10.1074/jbc.275.8.5958>
41. Tvrdík, D., Djaborkhel, R., Nagy, A., Eckschlager, T., Raška, I., Müller, J. (2002) Cyclin D-CDK6 complex is targeted by p21 WAF1 in growth-arrested lymphoma cells. J. Struct. Biol. 140, 49-56.
42. Tvrdík, D., Dundr, P., Povýšil, C., Pytlík, R., Planková, M. (2006) Up-regulation of p21 WAF1 expression is mediated by Sp1/Sp3 transcription factors in TGFβ1-arrested malignant B cells. Med. Sci. Monit. 12, 227-234.
43. Ushmorov, A., Debatin, K. M., Beltinger, C. (2005) Growth inhibition of murine neuroblastoma cells by c-myc with cell cycle arrest in G2/M. Cancer Biol. Ther. 4, 181-186. <https://doi.org/10.4161/cbt.4.2.1439>
44. Weith, A., Brodeur, G. M., Bruns, G. A., Matise, T. C., Mischke, D., Nizetic, D., Seldin, M. F., van Roy, N., Vance, J. (1996) Report of the second international workshop on human chromosome 1 mapping 1995. Cytogenet. Cell Genet. 72, 114-144. <https://doi.org/10.1159/000134173>
45. Young, N., Chang, Z., Wishart, D. S. (2004) GelScape: a web-based server for interactively annotating, manipulating, comparing and archiving 1D and 2D gel images. Bioinformatics 20, 976-978. <https://doi.org/10.1093/bioinformatics/bth033>
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