Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

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Fol. Biol. 2000, 46, 25-29

https://doi.org/10.14712/fb2000046010025

SHR.BN-Congenic Strains for Genetic Analysis of Multifactorially Determined Traits

V. Křen1,2, D. Křenová1, M. Šimáková2, A. Musilová2, V. Zídek2, Michal Pravenec1,2

1Institute of Biology and Medical Genetics, 1st Medical Faculty, Charles University, Prague, Czech Republic
2Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

References

1. Aitman, T. J., Gotoda, T., Evans, A. L., Imrie, H., Heath, K., Trembling, P., Truman, H., Wallace, C., Doré, C., Flint, J., Křen, V., Kurtz, T. W., Zídek, V., Pravenec, M., Scott, J. (1997) Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Nat. Genet. 16, 197-201. <https://doi.org/10.1038/ng0697-197>
2. Aitman, T. J., Glazier, A. M., Wallace, C. A., Cooper, L. D., Norsworthy, P. J., Wahid, F. N., Al-Majali, K. M., Trembling, P. M., Mann, C. J., Shoulders, C. C., Graf, D., St Lezin, E., Kurtz, T. W., Křen, V., Pravenec, M., Ibrahimi, A., Abumrad, N. A., Stanton, L. W., Scott, J. (1999) Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat. Genet. 21, 76-83. <https://doi.org/10.1038/5013>
3. Bílá, V., Křen, V. (1996) The teratogenic action of retinoic acid in rat congenic and recombinant inbred strains. Folia Biol. (Praha) 42, 167-173.
4. Darvasi, A., Soller, M. A. (1997) A simple method to calculate resolving power and confidence interval of QTL map location. Behav. Genet. 27, 125-32. <https://doi.org/10.1023/A:1025685324830>
5. Febraio, M., Abumrad, N. A., Hajjar, D. P., Sharma, K., Cheng, W., Pearce, S. F. A., Silverstein, R. L. (1999) A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J. Biol. Chem. 274, 19055-19062. <https://doi.org/10.1074/jbc.274.27.19055>
6. Hedrich, H. J. (ed)(1990) Genetic Monotoring of Inbred Strains, Gustav Fischer Verlag, Stuttgart, New York.
7. Ibrahimi, A., Bonen, A., Blinn, W. D., Hajri, T., Li, X., Zhong, K., Cameron, R., Abumrad, N. A. (1999) Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduced plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J. Biol. Chem. 274, 26761-26766. <https://doi.org/10.1074/jbc.274.38.26761>
8. Křen, V. (1975) Genetics of the polydactyly-luxate syndrome in the Norway rat, Rattus norvegicus. Acta Univ. Carol. Med. (Monogr.) 68, 1-103.
9. Křen, V., Křenová, D., Pravenec, M., Zdobinská, M. (1995) Chromosome 8 congenic strains: tools for genetic analysis of limb malformation, plasma triglycerides, and blood pressure in the rat. Folia Biol. (Praha) 41, 284-293.
10. Křen, V., Bílá, V., Kašpárek, R., Křenová, D., Pravenec, M., Rapp, K. (1996) Recombinant inbred and congenic strains of the rat for genetic analysis of limb morphogenesis. Folia Biol. (Praha) 42, 163-170.
11. Křen, V., Pravenec, M., Lu, S., Křenová, D., Wang, J.-M., Wang, N., Merriouns, T., Wong, A., St. Lezin, E., Lau, D., Szpirer, C., Szpirer, J., Kurtz, T. W. (1997) Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. J. Clin. Invest. 99, 577-581. <https://doi.org/10.1172/JCI119198>
12. Křen, V., Bílá, V., Kašpárek, R., Křenová, D. (1999) A new set of recombinant inbred strains complementary to HXB and BXH sets. J. Exp. Anim. Sci. 40, 51-53. <https://doi.org/10.1016/S0939-8600(99)80009-1>
13. Křenová, D., Kurtz, T. W., Wang, J.-M., Pravenec, M., Křen, V. (1997) Map of differential segment of rat chromosome 8 in SHR.Lx congenic strain. Transplant. Proc. 29, 1769. <https://doi.org/10.1016/S0041-1345(97)00049-3>
14. Křenová, D., Šoltysová, L., Pravenec, M., Kurtz, T. W., Moisan, M.-P., Křen, V. (1999) Putative candidate genes for blood pressure control in the SHR.BN-RNO8 congenic substrains. J. Exp. Anim. Sci. 40, 48-50.
15. Nadeau, J. H. (1999) Rattus norvegicus and the industrial revolution. Nat. Genet. 22, 3-4. <https://doi.org/10.1038/8703>
16. Okamoto, K., Aoki, K. (1963) Development of a strain of spontaneously hypertensive rats. Jpn. Circ. J. 27, 282-293. <https://doi.org/10.1253/jcj.27.282>
17. Pravenec, M., Klír, P., Křen, V., Zicha, J., Kuneš, J. (1989) An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains. J. Hypertens. 7, 217-222. <https://doi.org/10.1097/00004872-198903000-00008>
18. Pravenec, M., Gauguier, D., Schott, J.-J., Buard, J., Křen, V., Bílá, V., Szpirer, C., Szpirer, J., Wang, J., Huang, H., St. Lezin, E., Spence, M. A., Floodman, P., Printz, M., Lathrop, M., Vergnaud, G., Kurtz, T. W. (1995) Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains. J. Clin. Invest. 96, 1973-1978. <https://doi.org/10.1172/JCI118244>
19. Pravenec, M., Křen, V., St. Lezin, E. (1999) Recombinant inbred and congenic strains for genetic analysis of spontaneous hypertension and other risk factors of cardiovascular disease. In: Handbook of Hypertension, eds. W. H. Birkenhager, J. L. Reid, series, Development of the Hypertensive Phenotype: Basic and Clinical Studies, eds. R. McCarty, D. A. Blizard, R. L. Chevalier, pp. 193-211, Elsevier Science B. V., Amsterdam.
20. Pravenec, M., Křen, V., Křenová, D., Bílá, V., Zídek, V., Musilová, A., van Lith, H., van Zutphen, L. F. M. (1999a) HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles. Folia Biol. (Praha) 45, 203-215.
21. Pravenec, M., Zídek, V., Šimáková, M., Křen, V., Křenová, D., Horký, K., Jáchymová, M., Míková, B., Kazdová, L., Aitman, T. J., Churchill, P. C., Hingarh, N. H., Yang, Y., Wang, J.-M., St. Lezin, E. M., Kurtz, T. W. (1999b) Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension. J. Clin. Invest. 103, 1651-1657. <https://doi.org/10.1172/JCI6691>
22. Pravenec, M., Křen, V., Křenová, D., Zídek, V., Wang, J.-M., Kurtz, T. W., St. Lezin, E. (1999c) Derivation of SHR-chromosome 4 congenic sublines for fine genetic mapping of quantitative trait loci with major effects on insulin resistance and blood pressure. J. Exp. Anim. Sci. 40, 41-43. <https://doi.org/10.1016/S0939-8600(99)80002-9>
23. Qi, N., Křen, V., Pravenec, M., Zídek, V., Křenová, D., Kurtz, T. W. (1999) Transfer of the Y chromosome from the Brown Norway rat into the SHR induces significant decreases in blood pressure. Am. J. Hypertens. 12 (Pt 2), 16A (abstract). <https://doi.org/10.1016/S0895-7061(99)80054-5>
24. Steen, R. G., Kwitek-Black, A. E., Glenn, C., Gullings-Handley, J., Van Etten, W., Atkinson, O. S., Appel, D., Twigger, S., Muir, M., Mull, T., Granados, M., Kissebah, M., Russo, K., Crane, R., Popp, M., Peden, M., Matise, T., Brown, D. M., Lu, J., Kingsmore, S., Tonellato, P. J., Rozen, S., Slonim, D., Young, P., Knoblauch, M., Provoost, A., Ganten, D., Colman, S. D., Rothberg, J., Lander, E. S., Jacob, H. J. (1999) A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. Genome Res. 9, AP1-8. <https://doi.org/10.1101/gr.9.6.AP1>
25. St. Lezin, E., Liu, W., Wang, J.-M., Wang, N., Křen, V., Křenová, D., Musilová, A., Zdobinská, M., Zídek, V., Lau, D., Pravenec, M. (1997) Genetic dissection of hypertension by partial chromosome transfer: evidence of a role for rat chromosome 1 in the pathogenesis of spontaneous hypertension. Hypertension 30, 854-859. <https://doi.org/10.1161/01.HYP.30.4.854>
26. St. Lezin, E., Liu, W., Wang, N., Wang, J.-M., Křen, V., Zídek, V., Zdobinská, M., Křenová, D., Bottger, A., van Zutphen, B. F. M., Pravenec, M. (1998) Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat. Hypertension 31 (Pt 2), 373-7. <https://doi.org/10.1161/01.HYP.31.1.373>
27. St. Lezin, E., Zhang, L., Yang, Y., Wang, J.-M., Wang, N., Qi, N., Liu, W., Křen, V., Zídek, V., Křenová, D., Churchill, P. C., Churchill, M. C., Kurtz, T. W., Pravenec, M. (1999) Effect of chromosome 19 transfer on blood pressure in the spontaneously hypertensive rat. Hypertension 33 (Pt 2), 256-260. <https://doi.org/10.1161/01.HYP.33.1.256>
28. St. Lezin, E., Liu, W., Wang, J., Yang, Y., Qi, N., Křen, V., Zídek, V., Kurtz, T. W., Pravenec, M. (2000) Genetic analysis of rat chromosome 1 and the Sa gene in the pathogenesis of spontaneous hypertension. Hypertension (in press).
29. Watanabe, T. K,, Bihoreau, M. T., McCarthy, L. C., Kiguwa, S. L., Hishigaki, H., Tsuji, A., Browne, J., Yamasaki, Y., Mizoguchi-Miyakita, A., Oga, K., Ono, T., Okuno, S., Kanemoto, N., Takahashi, E., Tomita, K., Hayashi, H., Adachi, M., Webber, C., Davis, M., Kiel, S., Knights, C., Smith, A., Critcher, R., Miller, J., Thangarajah, T., Day, P. J. R., Hudson Jr., J. R., Irie, Y., Takagi, T., Nakamura, Y., Goodfellow, P. N., Tanigami, A., James, M. R. (1999) A radiation hybrid map of the rat genome containing 5,255 markers. Nat. Genet. 22, 27-36. <https://doi.org/10.1038/8737>
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