Fol. Biol. 2003, 49, 142-146
https://doi.org/10.14712/fb2003049040142
Interferon Inducibility of STAT 1 Activation and Its Prognostic Significance in Melanoma Patients
References
1. , T., Garcia, R., Turkson, J., Jove, R. (2000) STATs in oncogenesis. Oncogene 19, 2474-2488.
<https://doi.org/10.1038/sj.onc.1203527>
2. , M., Leaman, D. W., Jacobs, B. S., Tuthill, R. J., Chatterjee-Kishore, M., Stark, G. R., Borden, E. C. (2002) Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (Stat1). J. Interferon Cytokine Res. 22, 603-613.
<https://doi.org/10.1089/10799900252982089>
3. , T., Kovarik, P. (2000) Serine phosphorylation of STATs. Oncogene 19, 2628-2637.
<https://doi.org/10.1038/sj.onc.1203481>
4. , J. E., Hackenmiller, R., Simon, M. C., Levy, D. E. (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84, 443-450.
<https://doi.org/10.1016/S0092-8674(00)81289-1>
5. , D. A. (1999) STAT signaling in the pathogenesis and treatment of cancer. Mol. Med. 5, 432-456.
<https://doi.org/10.1007/BF03403538>
6. , R., Bowman, T. L., Niu, G., Yu, H., Minton, S., MuroCacho, C. A., Cox, C. E., Falcone, R., Fairclough, R., Parsons, S., Laudano, A., Gazit, A., Levitzki, A., Kraker, A., Jove, R. (2001) Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20, 2499-2513.
<https://doi.org/10.1038/sj.onc.1204349>
7. Klein, J. P., Moeschberger, M. L. (1997) Survival Analysis. Techniques for Censored and Truncated Data, pp. 502, Springer-Verlag, New York.
8. , P., Mangold, M., Ramsauer, K., Heidari, H., Steinborn, R., Zotter, A., Levy, D. E., Muller, M., Decker, T. (2001) Specificity of signaling by STAT 1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. EMBO J. 20, 91-100.
<https://doi.org/10.1093/emboj/20.1.91>
9. , D. E. (1999) Physiological significance of STAT proteins: investigations through gene disruption in vivo. Cell. Mol. Life Sci. 55, 1559-1567.
<https://doi.org/10.1007/s000180050395>
10. , M. A., White, J. M., Sheehan, K. C., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M., Schreiber, R. D. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAKSTAT signaling pathway. Cell 84, 431-442.
<https://doi.org/10.1016/S0092-8674(00)81288-X>
11. , J. J., Gadina, M., Schreiber, R. D. (2002) Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109, Suppl. S121-S131.
<https://doi.org/10.1016/S0092-8674(02)00701-8>
12. , A., Hildebrand, P., Fasler-Kan, E., Baselgia, L., Ketterer, S., Beglinger, C., Heim, M. H. (2000) Defective JAK-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha. Int. J. Cancer 85, 720-725.
<https://doi.org/10.1002/(SICI)1097-0215(20000301)85:5<720::AID-IJC20>3.0.CO;2-O>
13. , C. V., Gil, M. P., Han, Y., Ransohoff, R. M., Schreiber, R. D., Stark, G. R. (2001) Stat1-independent regulation of gene expression in response to IFN-gamma. Proc. Natl. Acad. Sci. USA 98, 6674-6679.
<https://doi.org/10.1073/pnas.111164198>
14. , C. V., Gil, M. P., Schreiber, R. D., Stark, G. R. (2002) Stat1-dependent and -independent pathways in IFNgamma-dependent signaling. Trends Immunol. 23, 96-101.
<https://doi.org/10.1016/S1471-4906(01)02118-4>
15. , G. R., Kerr, I. M., Williams, B. R., Silverman, R. H., Schreiber, R. D. (1998) How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264.
<https://doi.org/10.1146/annurev.biochem.67.1.227>
16. , C. J., Miller, W. R. (1995) Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts. Br. J. Cancer 71, 840-844.
<https://doi.org/10.1038/bjc.1995.162>
17. , Z., Zhong, Z., Darnell, J. E. Jr. (1995) Maximal activation of transcription by STAT 1 and STAT 3 requires both tyrosine and serine phosphorylation. Cell 82, 241-250.
<https://doi.org/10.1016/0092-8674(95)90311-9>
18. , A., Tonko-Geymayer, S., Welte, T., Daxenbichler, G., Marth, C., Doppler, W. (2002) Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin. Cancer Res. 8, 3065-3074.
19. , L. H., Krauer, K. G., Hatzinisiriou, I., Estcourt, M. J., Hersey, P., Tam, N. D., Edmondson, S., Devenish, R. J., Ralph, S. J. (1997) Interferon-resistant human melanoma cells are deficient in ISGF 3 components, STAT 1, STAT 2, and p48-ISGF 3gamma. J. Biol. Chem. 272, 28779-28785.
<https://doi.org/10.1074/jbc.272.45.28779>
20. , Y., Wang, S., Gobl, A., Oberg, K. (2001) Interferon alpha induction of Stat1 and Stat2 and their prognostic significance in carcinoid tumors. Oncology 60, 330-338.
<https://doi.org/10.1159/000058529>
