Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

Crossref logo

Fol. Biol. 2003, 49, 230-234

https://doi.org/10.14712/fb2003049060230

MHC Class I+ and Class I- HPV16-Associated Tumours Expressing the E7 Oncoprotein Do Not Cross-react in Immunization/Challenge Experiments

Jana Šímová1, R. Mikyšková1, V. Vonka2, J. Bieblová1, J. Bubeník1, T. Jandlová1

1Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
2Institute of Haematology and Blood Transfusion, Prague, Czech Republic

Received September 2003
Accepted November 2003

References

1. Bubeník, J., Šímová, J., Hájková, R., Sobota, V., Jandlová, T., Šmahel, M., Sobotková E., Vonka, V. (1999) Interleukin 2 gene therapy of residual disease in mice carrying tumours induced by HPV16. Int. J. Oncol. 14, 593-597.
2. Bubeník, J. (2002a) Animal models for development of therapeutic HPV16 vaccines. Int. J. Oncol. 20, 207-212.
3. Bubeník, J. (2002b ) Therapeutic vaccines against HPV16associated tumors. Neoplasma 49, 285-289.
4. Bubeník, J. (2003) Prospects for immunotherapy of MHC class I-deficient tumours. Folia Biol. (Praha) 49, 95-99.
5. Bubeník, J. (2003) Tumour MHC class I downregulation and immunotherapy. Oncol. Rep. 10, 2005-2008.
6. Chen, L., Thomas, E. K., Hu, S.-L., Hellstrom, I., Hellstrom, K. E. (1991) Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen. Proc. Natl. Acad. Sci. USA 88, 110-114. <https://doi.org/10.1073/pnas.88.1.110>
7. Indrová, M., Bubeník, J., Mikyšková, R., Vonka, V., Šmahel, M., Žák, R., Šímová J., Bieblová, J., Mendoza, L., Jandlová, T. (2002) Tumour-inhibitory and antimetastatic effects of IL-2 in mice carrying MHC class I- tumours of HPV16 origin. Int. J. Oncol. 20, 643-646.
8. Janoušková, O., Šíma, P., Kunke, D. (2003) Combined suicide gene and immunostimulatory gene therapy using AAV-mediated gene transfer to HPV-16 transformed mouse cell: decrease of oncogenicity and induction of protection. Int. J. Oncol. 22, 569-577.
9. Ji, H., Chang, E. Y., Lin, K.-Y., Kurman, R. J., Pardoll, D. M., Wu, T.-C. (1998) Antigen-specific immunotherapy for murine lung metastastic tumors expressing human papillomavirus type 16 E7 oncoprotein. Int. J. Cancer 78, 41-45. <https://doi.org/10.1002/(SICI)1097-0215(19980925)78:1<41::AID-IJC8>3.0.CO;2-X>
10. Jinoch, P., Žák, R., Janoušková, O., Kunke, D., Rittich, S., Dušková, M., Sobotková, E., Marinov, I., Andelová, M., Šmahel, M., Vonka, V. (2003) Immunization with live HPV16-transformed mouse cells expressing the herpes simplex thymidine kinase and either GM-CSF or IL-2. Int. J. Oncol. 23, 775-783.
11. Koutsky, L. A., Ault, K. A., Wheeler, C. M., Brown, D. R., Barr, E., Alvarez, F. B., Chiacchierini, L. M., Jansen, K. U. (2002) A controlled trial of a human papillomavirus type 16 vaccine. N. Engl. J. Med. 347, 1645-1651. <https://doi.org/10.1056/NEJMoa020586>
12. Levitsky, H. I., Lazenby, A., Hayashi, R. J., Pardoll, D. M. (1994) In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression. J. Exp. Med. 179, 1215-1224. <https://doi.org/10.1084/jem.179.4.1215>
13. Lin, K.-Y., Guarnieri, F. G., Staveley-O'Carroll, K. F., Levitsky, H. I., August, J. T., Pardoll, D. M., Wu, T.-C. (1996) Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Res. 56, 21-26.
14. Mikyšková, R., Bieblová, J., Šímová, J., Indrová, M., Jandlová, T., Vonka, V., Šmahel, M., Bubeník, J., Mendoza, L. (2003) Local IFN-γ therapy of HPV16-associated tumours. Folia Biol. (Praha) 49, 26-32.
15. Munoz, N., Bosch, F. X., de Sanjosé, S., Herrero, R., Castellsagué, X., Shah, K. V., Snijders, P. J. F., Meijer, C. J. L. M. (2003) Epidemiologic classification of human papillomavirus types associated with cervical cancer. N. Engl. J. Med. 348, 518-527. <https://doi.org/10.1056/NEJMoa021641>
16. Němečková, Š., Stránská, R., Šubrtová, J., Kutinová, L., Otáhal, P., Hainz, P., Marešová, L., Šroller, V., Hamšíková, E., Vonka, V. (2002) Immune response to E7 protein of human papillomavirus type 16 anchored on the cell surface. Cancer Immunol. Immunother. 51, 111-119. <https://doi.org/10.1007/s00262-001-0261-3>
17. Šmahel, M., Šíma, P., Ludvíková, V., Vonka, V. (2001) Modified HPV 16 E7 genes as DNA vaccine against E7 containing cells. Virology 281, 231-238. <https://doi.org/10.1006/viro.2000.0794>
18. Šmahel, M., Šíma, P., Ludvíková, V., Marinov, I., Pokorná, D., Vonka, V. (2003) Immunization with modified HPV 16 E7 genes against oncogenic TC-1 sublines with downregulated expression of MHC class I molecules. Vaccine 21, 1125-1136. <https://doi.org/10.1016/S0264-410X(02)00519-4>
19. Waggoner, S. E. (2003) Cervical cancer. Lancet 361, 2217-2225. <https://doi.org/10.1016/S0140-6736(03)13778-6>
20. Zur Hausen, H. (2001) Oncogenic DNA viruses. Oncogene 26, 7820-7823. <https://doi.org/10.1038/sj.onc.1204958>
21. Zwaveling, S., Mota, S. C. F., Nouta, J., Johnson, M., Lipford, G. B., Offringa, R., van der Burg, S. H., Melief, C. J. M. (2002) Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J. Immunol. 169, 350-358. <https://doi.org/10.4049/jimmunol.169.1.350>
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive