Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

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Fol. Biol. 2005, 51, 82-84

https://doi.org/10.14712/fb2005051030082

The Effect of Gemcitabine in the Treatment of Rejection in Experimental Small Intestine Transplantation

Michal Kudla1, J. Kříž2, D. Janotová3, P. Girman2, H. Mergental1, M. Kočík1, E. Honsová3, M. Adamec1

1Department of Transplant Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
2Centre of Diabetes, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
3Department of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

Received May 2005
Accepted May 2005

References

1. Goulet, O., Lacaille, F., Jan, D., Ricour, C. (2000) Intestinal transplantation: indications, results and strategy. Curr. Opin. Clin. Nutr. Metab. 3, 329-338. <https://doi.org/10.1097/00075197-200009000-00002>
2. Grant, D. (1997) Intestinal transplantation: 1997 report of the international registry. Transplantation 67, 1061-1064. <https://doi.org/10.1097/00007890-199904150-00021>
3. Jeske, H. C., Oberladstätter, J., Schneeberger, S., Hittmair, A., Klima, G., Obrist, P., Öllinger, R., Roberts, K., Schubert, H., Steurer, W., Margreiter, R. (2003) Gemcitabine with cyclosporine or with tacrolimus exerts a synergistic effect and induces tolerance in rat. Transplantation 76, 1046-1052. <https://doi.org/10.1097/01.TP.0000090544.17227.57>
4. Jung, F., Wilker, S., Maas, E., Berendel, M. D., Grimm, H., Korom, S. (2002) Gemcitabine in models of acute and accelerated rejection. Transpl. Proc. 34, 1420-1421. <https://doi.org/10.1016/S0041-1345(02)02911-1>
5. Margreiter, R., Fischer, M., Roberts, K., Schmidt, T., Hittmair, A., Schirmer, M., Geisen, F., Tiefenthaler, M., Konwalinka, G. (1999) Gemcitabine – a novel immunosuppressive agent prevents rejection in a rat cardiac transplantation model. Transplantation 68, 1051-1053. <https://doi.org/10.1097/00007890-199910150-00025>
6. McDiarmid, S. V., Farmer, D. G., Kuniyoshi, J. S., Robert, M., Khadavi, A., Shaked, A., Busuttil, R. W. (1994) The correlation of intragraft cytokine expression with rejection in rat small intestine transplantation. Transplantation 58, 690-697. <https://doi.org/10.1097/00007890-199409270-00009>
7. Mergental, H., Kriz, J., Honsova, E., Kudla, M., Pantoflicek, T., Tscherentsova, E., Kocik, M., Saudek, F., Ryska, M. (2005) Gemcitabine does not prevent acute rejection of the transplanted liver in rats. Transpl. Int. 17, 687-691. <https://doi.org/10.1007/s00147-004-0752-1>
8. Monchik, G. J., Russell, P. S. (1971) Transplantation of small bowel in the rat: Technical and immunological considerations. Surgery 70, 693-702.
9. Plunkett, W., Gandhi, V., Chubb, S. (1989) 2’2’-difluorodeoxycytidine metabolism and mechanism of action in human leukemia cells. Nucleotides 8, 775.
10. Plunkett, W., Huang, P., Gandhi, V. (1995) Preclinical characteristics of gemcitabine. Anticancer Drugs 6 (Suppl. 6), 7-13. <https://doi.org/10.1097/00001813-199512006-00002>
11. Ricordi, C., Murase, N., Rastellini, C., Behboo, R., Demetris, A. J., Starzl, T. E. (1995) Indefinite survival of rat islet allografts following infusions of donor bone marow without cytoablation. Cell Transplant. 5, 53-55. <https://doi.org/10.1177/096368979600500110>
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