Fol. Biol. 2010, 56, 173-182
https://doi.org/10.14712/fb2010056040173
The Autophagy-Lysosomal Pathway Is Involved in TAG Degradation in the Liver: the Effect of High-Sucrose and High-Fat Diet
References
1. , G., Krauss, R. M., Fredrickson, D. S., Levy, R. I. (1973) Characterization, subcellular localization, and partial purification of a heparin-released triglyceride lipase from rat liver. J. Biol. Chem. 248, 1992-1999.
<https://doi.org/10.1016/S0021-9258(19)44177-X>
2. , P., Vaughan, M. (1969) Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. J. Lipid Res. 10, 341-344.
<https://doi.org/10.1016/S0022-2275(20)43094-9>
3. , B., Spee, B., Rothuizen, J., Penning, L. C. (2006) Development and evaluation of canine reference genes for accurate quantification of gene expression. Anal. Biochem. 356, 36-43.
<https://doi.org/10.1016/j.ab.2006.06.001>
4. , L. J., Thomas, J., De Schepper, P. J., Mannaerts, G. P. (1979) Lysosomal triacylglycerol lipase and lipolysis in isolated rat hepatocytes. J. Biol. Chem. 254, 8841-8846.
<https://doi.org/10.1016/S0021-9258(19)86776-5>
5. , V. W., Gilham, D., Alam, M., Vance, D. E., Lehner, R. (2004) Triacylglycerol hydrolase: role in intracellular lipid metabolism. Cell. Mol. Life Sci. 61, 1633-1651.
<https://doi.org/10.1007/s00018-004-3426-3>
6. , H., Heur, M., Duanmu, M., Grabowski, G. A., Hui, D. Y., Witte, D. P., Mishra, J. (2001) Lysosomal acid lipasedeficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span. J. Lipid Res. 42, 489-500.
<https://doi.org/10.1016/S0022-2275(20)31157-3>
7. , J., Lees, M., Sloane Stanley, G. H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509.
<https://doi.org/10.1016/S0021-9258(18)64849-5>
8. , O. L., Griffaton, G., Kalopissis, A. D. (1992) Effect of a high-fat diet on the incorporation of stored triacylglycerol into hepatic VLDL. Am. J. Physiol. Endocrinol. Metab. 263, E615-E623.
<https://doi.org/10.1152/ajpendo.1992.263.4.E615>
9. , G. F., Wiggins, D. (1995) Intracellular triacylglycerol lipase: its role in the assembly of hepatic very-low-density lipoprotein (VLDL). Adv. Enzyme Regul. 35, 179-198.
<https://doi.org/10.1016/0065-2571(94)00006-O>
10. , D., Ho, S., Rasouli, M., Martres, P., Vance, D. E., Lehner, R. (2003) Inhibitors of hepatic microsomal hydrolase decrease very low density lipoprotein secretion. FASEB J. 17, 1685-1697.
<https://doi.org/10.1096/fj.02-0728fje>
11. , D. J., Cuervo, A. M., Seglen, P. O. (2007) Methods for monitoring autophagy from yeast to human. Autophagy 3, 181-206.
<https://doi.org/10.4161/auto.3678>
12. , N., Kapoor, S., Enami, Y., Follenzi, A., Bandi, S., Joseph, B., Gupta, S. (2009) Hepatocyte transplantationinduced liver inflammation is driven by cytokines-chemokines associated with neutrophils and Kupffer cells. Gastroenterology 136, 1806-1817.
<https://doi.org/10.1053/j.gastro.2009.01.063>
13. , D. L., Brown, A. M., Zammit, V. A (1998) Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes. J. Lipid Res. 39, 1889-1895.
<https://doi.org/10.1016/S0022-2275(20)32177-5>
14. , R., Verger, R (1997) Purification and characterization of a porcine liver microsomal triacylglycerol hydrolase. Biochemistry 36, 1861-1868.
<https://doi.org/10.1021/bi962186d>
15. , R., Cui, Z., Vance, D. E. (1999) Subcellullar localization, developmental expression and characterization of a liver triacylglycerol hydrolase. Biochem. J. 338(Pt 3), 761-768.
<https://doi.org/10.1042/bj3380761>
16. , Z., Berc, M., McIntyre, T., Gores, G., Feldstein, A. (2008) The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity. Hepatology 47, 1495-1503.
<https://doi.org/10.1002/hep.22183>
17. , J. D., Foster, D. W. (1980) Regulation of hepatic fatty acid oxidation and ketone body production. Annu. Rev. Biochem. 49, 395-420.
<https://doi.org/10.1146/annurev.bi.49.070180.002143>
18. , R. P., Plat, J., Schrauwen, P. (2008) Diet and nonalcoholic fatty liver disease. Curr. Opin. Lipidol. 19, 25-29.
<https://doi.org/10.1097/MOL.0b013e3282f382ea>
19. , L., Griffaton, G., Kalopissis, A. D. (1996) Hepatic VLDL secretion of genetically obese Zucker rats is inhibited by a high-fat diet. Am. J. Physiol. 271, E952-E964.
20. , D. C., Cuervo, A. M., Ravikumar, B., Sarkar, S., Korolchuk, V., Kaushik, S., Klionsky, D. J. (2009) In search of an “autophagomometer”. Autophagy 5, 585-589.
<https://doi.org/10.4161/auto.5.5.8823>
21. , V. T., Liu, Z. X., Qu, X., Elder, B. D., Bilz, S., Befroy, D., Romanelli, A. J., Shulman, G. I. (2004) Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J. Biol. Chem. 279, 32345-32353.
<https://doi.org/10.1074/jbc.M313478200>
22. , P. O., Solheim, A. E. (1985) Conversion of dense lysosomes into light lysosomes during hepatocytic autophagy. Exp. Cell Res. 157, 550-555.
<https://doi.org/10.1016/0014-4827(85)90141-7>
23. , R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M.,Tanaka,K.,Cuervo,A.M.,Czaja,M.J.(2009)Autophagy regulates lipid metabolism. Nature 458, 1131-1135.
<https://doi.org/10.1038/nature07976>
24. , Y., Harada, R., Himeno, M., Kato, K. (1990) Biosynthesis, processing, and intracellular transport of lysosomal acid phosphatase in rat hepatocytes. J. Biochem. 108, 278-286.
<https://doi.org/10.1093/oxfordjournals.jbchem.a123194>
25. , H., Mosinger, B. (1971) Effect of glucagon, catecholamines and insulin on liver acid lipase and acid phosphatase. Biochim. Biophys. Acta 231, 320-326.
<https://doi.org/10.1016/0005-2760(71)90145-7>
26. , E., Alam, M., Sun, F., Agellon, L., Vance, D. E., Lehner, R. (2007) Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice. J. Lipid Res. 48, 2597-2606.
<https://doi.org/10.1194/jlr.M700320-JLR200>
27. , D., Gibbons, G. F. (1992) The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas. Biochem J. 284(Pt 2), 457-462.
<https://doi.org/10.1042/bj2840457>
28. , M., Yamamoto, I., Tanaka, Y., Ontko, J. A. (1987) Fatty acid metabolism and lipid secretion by perfused livers from rats fed laboratory stock and sucrose-rich diets. J. Lipid Res. 28, 1156-1165.
<https://doi.org/10.1016/S0022-2275(20)38605-3>
29. , L. Y., Kuksis, A., Myher, J. J., Steiner, G. (1995) Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies. J. Lipid Res. 36, 125-136.
<https://doi.org/10.1016/S0022-2275(20)39761-3>
