Fol. Biol. 2011, 57, 12-19

https://doi.org/10.14712/fb2011057010012

Oxidative Photodamage Induced by Photodynamic Therapy with Methoxyphenyl Porphyrin Derivatives in Tumour-Bearing Rats

D. Daicoviciu1, Adriana G. Filip1, R. M. Ion2, S. Clichici1, N. Decea1, A. Muresan1

1Department of Physiology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
2National R&D Institute of Chemistry and Petrochemistry – ICECHIM, Bucharest, Romania

Received July 2010
Accepted December 2010

References

1. Beauchamp, C., Fridovich, I. (1971) Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal. Biochem. 44, 276-282. <https://doi.org/10.1016/0003-2697(71)90370-8>
2. Chatterjee, S. R., Srivastava, T. S., Kamat, J. P., Devasagayam, T. P. A. (1997) Lipid peroxidation induced a novel porphyrin plus light in isolated mitochondria: possible implications in photodynamic therapy. Mol. Cell. Biochem. 166, 25-33. <https://doi.org/10.1023/A:1006840714583>
3. Chekulayeva, L. V., Shevchuk, I. N., Chekulayev, V. A. (2004) Influence of temperature on the efficiency of photodestruction of Ehrlich ascites carcinoma cells sensitized by hematoporphyrin derivative. Exp. Oncol. 26, 125-139.
4. Clichici, S., Filip, A., Daicoviciu, D., Ion, R. M., Mocan, T., Tatomir, C., Rogojan, L., Olteanu, D., Muresan, A. (2010) The dynamics of reactive oxygen species in photodynamic therapy with tetra sulfophenyl porphyrin. Acta Physiol. Hung. 97, 41-51. <https://doi.org/10.1556/APhysiol.97.2010.1.5>
5. Daicoviciu D., Filip A., Clichici S., Suciu S., Muresan A., Decea N., Dreve S. (2008) Oxidative effects after photodynamic therapy in rats. Bulletin UASVM Veterinary Medicine Cluj-Napoca 65, 364-369.
6. De Rosa, F., Bentley, M. V. L. B. (2000) Photodynamic therapy of skin cancers: sensitizers, clinical studies and future directives. Pharm. Res. 17, 1447-1455. <https://doi.org/10.1023/A:1007612905378>
7. Dougherty, T. J., Gomer, C. J., Henderson, B. W., Jori, G., Kesseli, D., Korbelik, M. (1998) Photodynamic therapy. J. Natl. Cancer Inst. 90, 889-905. <https://doi.org/10.1093/jnci/90.12.889>
8. El-Missiry, M. A., Abou-Seif, M. A. (2000) Photosensitization induced reactive oxygen species and oxidative damage in human erythrocytes. Cancer Lett. 158, 155-163. <https://doi.org/10.1016/S0304-3835(00)00513-9>
9. Esterbauer, H., Chjeeseman, K. (1994) Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186, 406-413.
10. Filip, A., Clichici, S., Muresan, A., Daicoviciu, D., Tatomir, C., Login, C., Dreve, S., Gherman, C. (2008) Effects of PDT with 5-aminolevulinic acid and chitosan on Walker carcinosarcoma. Exp. Oncol. 30, 212-218.
11. Flohe, L., Gunzler, W. (1984) Assays of glutathione peroxidase. Methods Enzymol. 105, 114-122. <https://doi.org/10.1016/S0076-6879(84)05015-1>
12. Girotti, A. W. (2001) Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms. J. Photochem. Photobiol. B Biol. 63, 103-113. <https://doi.org/10.1016/S1011-1344(01)00207-X>
13. Golab, J., Nowis, D., Skrzycki, M., Baranczyk-Kuzma, A., Wilczynski, G.,M., Makowski, M., Mroz, P., Kozar, K., Kaminski, R., Jalili, A., Kopec, M., Grzela, T., Jakobisiak, M. (2003) Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. J. Biol. Chem. 278, 407-414.
14. Gutteridge, J. M. C. (1995) Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin. Chem. 41, 1819-1828. <https://doi.org/10.1093/clinchem/41.12.1819>
15. Ion, R. M. (1993) Spectrophotometric study of the photodegradation reaction of the tetra-aryl-porphyrins. The mesosubstituent effect. Rev. Chim. (Bucharest) 44, 431-435.
16. Ion, R. M., Mandravel, C. (1996-1997) The photodegradation reaction of some porphyrins. South. Braz. J. Chem. Soc. V, 111-117.
17. Ion, R. M., Grigorescu, M. (1997) The synthesis computation of tetra-aryl-porphyrins. Rev. Chim. (Bucharest) 48, 324-328.
18. Ion, R. M. (2007) Photodynamic therapy (PDT): a photochemical concept with medical applications. Rev. Chim. (Bucharest) 52, 1093-1102.
19. Jakus, J., Farkas, O. (2005) Photosensitizers and antioxidants: a way to new drugs? Photochem. Photobiol. Sci. 4, 694-698. <https://doi.org/10.1039/b417254j>
20. Johnson, S. A. S., Pardini, R. S. (1998) Antioxidant enzyme response to hypericin in EMT6 mouse mammary carcinoma cells. Free Radic. Biol. Med. 24, 817-826. <https://doi.org/10.1016/S0891-5849(97)00364-X>
21. Jori, G. (1996) Tumor photosensitizers: approaches to enhance the selectivity and efficiency of photodynamic therapy. J. Photochem. Photobiol. B Biol. 36, 87-93. <https://doi.org/10.1016/S1011-1344(96)07352-6>
22. Magi, B., Ettore, A., Liberatori, S., Bini, L., Andreassi, M., Frosali, S., Neri, P., Pallini, V., Di Stefano, A. (2004) Selectivity of protein carbonylation in the apoptotic response to oxidative stress associated with photodynamic therapy: a cell biochemical and proteomic investigation. Cell Death. Differ. 11, 842-852. <https://doi.org/10.1038/sj.cdd.4401427>
23. Milanesio, M. E., Alvarez, M. G., Yslas, E. I., Borsarelli, C. D., Silber, J. J., Rivarola, V., Durantini, E. N. (2001) Photodynamic studies of metallo-5,10,15,20-tetrakis(4-methoxiphenyl) porphyrin: photochemical characterization and biological consequences in a human carcinoma cell line. Photochem. Photobiol. 74, 14-21. <https://doi.org/10.1562/0031-8655(2001)074<0014:PSOMTM>2.0.CO;2>
24. Noble, J. E., Bailey, M. J. A. (2009) Quantitation of protein. Methods Enzymol. 463, 72-95.
25. Nowis, D., Makowski, M., Stoklosa, T., Legat, M., Issat, T., Golab, J. (2005) Direct tumor damage mechanisms of photodynamic therapy. Acta Biochim. Pol. 52, 339-352. <https://doi.org/10.18388/abp.2005_3447>
26. Pippenger, C. E., Browne, R. W., Armstrong, D. (1998) Regulatory antioxidant enzymes. Methods Mol. Biol. 108, 299-311.
27. Price, M., Terlecky, S. R., Kessel, D. (2009) A role of hydrogen peroxide in the pro-apoptotic effects of photodynamic therapy. Photochem. Photobiol. 85, 1491-1496. <https://doi.org/10.1111/j.1751-1097.2009.00589.x>
28. Re, R., Pellegrini, N., Protegente, A., Pannala, A., Yang, M., Rice-Evans, C. (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic. Biol. Med. 26, 1231-1237. <https://doi.org/10.1016/S0891-5849(98)00315-3>
29. Reznick, A. Z., Packer L. (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol. 233, 357-363. <https://doi.org/10.1016/S0076-6879(94)33041-7>
30. Saczko, J., Chwilkowska, A., Kulbacka, J., Berdowska, I., Zielinski, B., Drag-Zalezinska, M., Wysocka, T., Lugowski, M., Banas, T. (2008) Photooxidative action in cancer and normal cells induced by the use of photofrin in photodynamic therapy. Folia Biol. (Praha) 54, 24-29.
31. Saczko, J., Skrzypek, W., Chwilkowska, A., Choromanska, A., Pola, A., Gamian, A., Kulbacka, J. (2009) Photo-oxidative action in cervix carcinoma cells induced by HPD-mediated photodynamic therapy. Exp. Oncol. 31, 195-199.
32. Sakharov, V. D., Bunschoten, A., van Weelden, H., Wirtz, K. W. A. (2003) Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation. Eur. J. Biochem. 270, 4859-4865. <https://doi.org/10.1046/j.1432-1033.2003.03885.x>
33. Streckyte, G., Didziapetriene, J., Grazeliene, G., Prasmickiene, G., Sukeliene, D., Kazlauskaite, N., Characiejus, D., Griciute, L., Rotomskis, R. (1999) Effects on photodynamic therapy in combination with Adriamycin. Cancer Lett. 146, 73-86. <https://doi.org/10.1016/S0304-3835(99)00241-4>
34. Tsaytler, P. A., O’Flaherty, M. C., Sakharov, D. V., Krijgsveld, J., Egmond, M. R. (2008) Immediate protein targets of photodynamic treatment in carcinoma cells. J. Proteome Res. 7, 3868-3878. <https://doi.org/10.1021/pr800189q>
35. Uneri, C., Sari, M., Baglam, T., Polat, S., Yuksel, M. (2006) Effects of vitamin E on cigarette smoke induced oxidative damage in larynx and lung. Laryngoscope 116, 97-100. <https://doi.org/10.1097/01.mlg.0000186504.53216.d1>
36. Wardman, P. (2007) Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: Progress, pitfalls, and prospects. Free Radic. Biol. Med. 43, 995-1022. <https://doi.org/10.1016/j.freeradbiomed.2007.06.026>
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