Fol. Biol. 2013, 59, 146-153
https://doi.org/10.14712/fb2013059040146
Selective Depletion of Alloreactive Donor T Cells Leads to Elimination of Graft-Versus-Host Reactivity and Stimulates Graft-Versus-Leukaemia/Myeloma Effect
References
1. 2006) Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Blood 108, 1797-1808.
< , P. J., Muccioli-Casadei, G., Huls, H., Adams, S., Durett, A., Gee, A., Yvon, E., Weiss, H., Cobbold, M., Gaspar, H. B., Rooney, C., Kuehnle, I., Ghetie, V., Schindler, J., Krance, R., Heslop, H. E., Veys, P., Vitetta, E., Brenner, M. K. (https://doi.org/10.1182/blood-2006-02-001909>
2. 2011) Setting the standard in T-cell-depleted haploidentical transplantation and beyond. Best Pract. Res. Clin. Haematol. 24, 325-329.
< F. (https://doi.org/10.1016/j.beha.2011.04.008>
3. 2010) Relapse after allogeneic stem cell transplantation. Expert Rev. Hematol. 3, 429-441.
< , A. J., Battiwalla M. (https://doi.org/10.1586/ehm.10.32>
4. 2012) Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. Blood 119, 5030-5036.
< , A., Patterson, S., Szydlo, R., Chaudhry, M. S., Dazzi, F., Kanfer, E., McDonald, D., Marin, D., Milojkovic, D., Pavlu, J., Davis, J., Rahemtulla, A., Rezvani, K., Goldman, J., Roberts, I., Apperley, J., Karadimitris, A. (https://doi.org/10.1182/blood-2011-11-389304>
5. 2002) Prevention of graft-versus-host disease while preserving graft-versusleukemia effect after selective depletion of host-reactive T cells by photodynamic cell purging process. Blood 99, 3083-3088.
< , B. J., Cui, X., Liu, C., Chao, N. J. (https://doi.org/10.1182/blood.V99.9.3083>
6. 1999) Pathophysiologic mechanisms of acute graft-vs.-host disease. Biol. Blood Marrow Transplant. 5, 347-356.
< , J. L., Levy, R., Chao, N. J. (https://doi.org/10.1016/S1083-8791(99)70011-X>
7. 2001) The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood 98, 3192-3204.
< , V. T., Soiffer, R. J. (https://doi.org/10.1182/blood.V98.12.3192>
8. 2004) Graft-versus-leukemia reactions in allogeneic chimeras. Blood 103, 767-776.
< , H. J., Schmid, C., Barrett, A. J., Schendel, D. J. (https://doi.org/10.1182/blood-2003-02-0342>
9. 1998) Specific depletion of alloreactive T cells in HLA-identical siblings: a method for separating graft-versus-host and graft-versus-leukemia reactions. Br. J. Haematol. 101, 565-570.
< , D. A., Dermime, S., Molldrem, J., Jiang, Y. Z., Raptis, A., van Rhee, F., Hensel, N., Fellowes, V., Eliopoulos, G., Barrett, A. J. (https://doi.org/10.1046/j.1365-2141.1998.00748.x>
10. 2000) The effect of chain immunotoxin different enhancers on the ability of an anti-CD25 ricin A to deplete cells which are activated in an MLR. Blood 96, 312b.
, J., Collins, R. H., Vitetta, E. S. (
11. 2003a) Definitive separation of graft-versus-leukemia and graft-versus-host specific CD4+ T cell clones by virtue of their T cell receptor beta locus sequences. Proc. Natl. Acad. Sci. USA 100, 1180-1184.
< , J., Collins, R. H., Durrani, H. P., Václavková, P., Ruff, L. E., Douek, D. C., Vitetta, E. S. (https://doi.org/10.1073/pnas.0337543100>
12. 2003b) Clinicalscale selective depletion of alloreactive T cells using an anti-CD25 immunotoxin. Neoplasma 50, 296-299.
, J., Collins, R. H., Vitetta, E. S. (
13. 2008) A clinical scale selective allodepletion approach for the treatment of HLAmismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique. Blood 111, 4392–4402.
< , S., Nunes, R., Rezvani, K. (https://doi.org/10.1182/blood-2007-08-104471>
14. 2011) Selectively T cell-depleted allografts from HLA-matched sibling donors followed by low-dose posttransplantation immunosuppression to improve transplantation outcome in patients with hematologic malignancies. Biol. Blood Marrow Transplant. 17, 1855-1861.
< , S., McIver, Z. A., Shenoy, A., Fellowes, V., Khuu, H., Stroncek, D. F., Leitman, S. F., Childs, R., Battiwalla, M., Koklanaris, E., Haggerty, J., Savani, B. N., Rezvani, K., Barrett, A. J. (https://doi.org/10.1016/j.bbmt.2011.05.019>
15. 2012) Comparative outcomes of donor graft CD34+ selection and immune suppressive therapy as graftversus-host disease prophylaxis for patients with acute myeloid leukemia in complete remission undergoing HLAmatched sibling allogeneic hematopoietic cell transplantation. J. Clin. Oncol. 30, 3194-3201.
< , M. C., Devine, S., Mendizabal, A., Baden, L. R., Wingard, J. R., Lazarus, H. M., Appelbaum, F. R., KeeverTaylor, C. A., Horowitz, M. M., Carter, S., O’Reilly, R. J., Soiffer, R. J. (https://doi.org/10.1200/JCO.2012.41.7071>
16. 2010) Drug-mediated and cellular immunotherapy in multiple myeloma. Immunotherapy 2, 243-255.
< , D. S., Quach, H., Fielding, K., Neeson, P. (https://doi.org/10.2217/imt.10.9>
17. 2005) Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation. Blood 106, 1123-1129.
< , S. R., Mielke, S., Savani, B. N. (https://doi.org/10.1182/blood-2005-01-0393>
18. 2006) A comparison of an anti-CD25 immunotoxin, Ontak and anti-CD25 microbeads for their ability to deplete alloreactive T cells in vitro. Bone Marrow Transplant. 37, 559-567.
< , P., Cao, Y., Wu, L. K., Michalek, J., Vitetta, E. S. (https://doi.org/10.1038/sj.bmt.1705286>
19. 1999) Selective depletion of major and minor histocompatibility antigen reactive T cells: towards prevention of acute graftversus-host disease. Br. J. Haematol. 107, 169-175.
< , A. M., Kessler, F. L., Stadhouders-Keet, S. A., Verdonck, L. F., de Gast, G. C., Otten, H. G. (https://doi.org/10.1046/j.1365-2141.1999.01675.x>
20. 2012) Graft-versus-host disease induced graft-versus-leukemia effect: greater impact on relapse and disease-free survival after reduced intensity conditioning. Biol. Blood Marrow Transplant. 18, 1727-1733.
< , D., Zhang, M. J., Arora, M., Horowitz, M. M., Rizzo, J. D., Eapen, M. (https://doi.org/10.1016/j.bbmt.2012.06.014>