Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

Crossref logo

Fol. Biol. 2013, 59, 217-224

https://doi.org/10.14712/fb2013059060217

Correlated Increase of Omentin-1 and Adiponectin by Exenatide, Avandamet and Dietary Change in Diet-Induced Obese Rats

W.-H. Feng1, X.-W. Yuan2, G.-Y. Tong1, W.-M. Wang1, Y. Hu1, S.-M. Shen1, P. Li1, Y. Bi1, J. Hu1, L.-L. Shao3, Y.-Y. Dai4, Y.-Q. Liu4, S.-K. Xiang5, D.-H. Yang1, Da-Long Zhu1

1Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing Medical University, Nanjing, China
2Department of Endocrinology, Nanjing Children’s Hospital Affiliated to Nanjing Medical University, Nanjing, China
3Nanjing University of Chinese Medicine, Nanjing, China
4Medical School of Southeast University, Nanjing, China
5Department of Endocrinology, Changzhou First People’s Hospital, Nanjing, China

Received September 30, 2013
Accepted October 24, 2013

References

1. Barnett, A. H. (2009) Redefining the role of thiazolidinediones in the management of type 2 diabetes. Vasc. Health Risk Manag. 5, 141-151. <https://doi.org/10.2147/VHRM.S4664>
2. Bonora, E., Targher, G., Alberiche, M., Bonadonna, R. C., Saggiani, F., Zenere, M. B., Monauni, T., Muggeo, M. (2000) Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 23, 57-63. <https://doi.org/10.2337/diacare.23.1.57>
3. Cicero, A. F., Tartagni, E., Ertek, S. (2012) Metformin and its clinical use: new insights for an old drug in clinical practice. Arch. Med. Sci. 8, 907-917. <https://doi.org/10.5114/aoms.2012.31622>
4. Cummings, B. P., Stanhope, K. L., Graham, J. L., Baskin, D. G., Griffen, S. C., Nilsson C, Sams, A., Knudsen, L. B, Raun, K., Havel, P. J. (2010) Chronic administration of the glucagon­like peptide­1 analog, liraglutide, delays the onset of diabetes and lowers triglycerides in UCD-T2DM rats. Diabetes 59, R2653-2661. <https://doi.org/10.2337/db09-1564>
5. de Souza Batista, C. M., Yang, R. Z., Lee, M. J., Glynn, N. M., Yu, D. Z., Pray J, Ndubuizu, K., Patil, S., Schwartz, A., Kligman, M., Fried, S. K., Gong, D. W., Shuldiner, A. R., Pollin, T. I., McLenithan, J. C. (2007) Omentin plasma levels and gene expression are decreased in obesity. Diabetes 56, 655-661. <https://doi.org/10.2337/db06-1506>
6. Gupta, M., Braga, M. B., Verma S. (2008) A randomized, controlled trial of the effects of rosiglitazone on adipokines, and inflammatory and fibrinolytic markers in diabetic patients: study design and protocol. Can. J. Cardiol. 24, e65-69. <https://doi.org/10.1016/S0828-282X(08)70685-8>
7. He, M., Su, H., Gao, W., Johansson, S. M., Liu, Q., Wu, X., Liao, J., Young, A. A., Bartfai, T., Wang, M. W. (2010) Reversal of obesity and insulin resistance by a non­peptidic glucagon­like peptide­1 receptor agonist in diet­induced obese mice. PLoS One 5, e14205. <https://doi.org/10.1371/journal.pone.0014205>
8. Kadoglou, N. P., Kapelouzou, A., Tsanikidis, H., Vitta, I., Liapis, C. D., Sailer, N. (2011) Effects of rosiglitazone/ metformin fixed-dose combination therapy and metformin monotherapy on serum vaspin, adiponectin and IL-6 levels in drug-naïve patients with type 2 diabetes. Exp. Clin. Endocrinol. Diabetes 119, 63-68. <https://doi.org/10.1055/s-0030-1265174>
9. Kadowaki, T., Yamauchi, T., Kubota, N., Hara, K., Ueki, K., Tobe, K. (2006) Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792. <https://doi.org/10.1172/JCI29126>
10. Li, L., Yang, G., Li, Q., Tan, X., Liu, H., Tang, Y., Boden, G. (2008) Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels. Diabetes Obes. Metab. 10, 921-930. <https://doi.org/10.1111/j.1463-1326.2007.00832.x>
11. Moreno-­Navarrete, J. M., Catalán, V., Ortega, F., Gómez-Ambrosi, J., Ricart, W., Frühbeck, G., Fernández­Real, J. M. (2010) Circulating omentin concentration increases after weight loss. Nutr Metab (Lond). 7, 27. <https://doi.org/10.1186/1743-7075-7-27>
12. Nordmann, A. J., Nordmann, A., Briel, M., Keller, U., Yancy, W. S. Jr., Brehm, B. J., Bucher, H. C. (2006) Effects of low- carbohydrate vs low­fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials. Arch. Intern. Med. 166, 285-293. <https://doi.org/10.1001/archinte.166.3.285>
13. Saremi, A., Asghari, M., Ghorbani, A. (2010) Effects of aerobic training on serum omentin­1 and cardiometabolic risk factors in overweight and obese men. J. Sports Sci. 28, 993-998. <https://doi.org/10.1080/02640414.2010.484070>
14. Sathyanarayana, P., Jogi, M., Muthupillai, R., Krishnamurthy, R., Samson, S. L., Bajaj, M. (2011) Effects of combined exenatide and pioglitazone therapy on hepatic fat content in type 2 diabetes. Obesity (Silver Spring) 19, 2310-2315. <https://doi.org/10.1038/oby.2011.152>
15. Shibata, R., Ouchi, N., Takahashi, R., Terakura, Y., Ohashi, K., Keda, N., Higuchi, A., Terasaki, H., Kihara, S., Murohara, T. (2012) Omentin as a novel biomarker of metabolic risk factors. Diabetol. Metab. Syndr. 26, 37. <https://doi.org/10.1186/1758-5996-4-37>
16. Shiraishi, D., Fujiwara, Y., Komohara, Y., Mizuta, H., Takeya, M. (2012) Glucagon-like peptide-1 (GLP-1) induces M2 polarization of human macrophages via STAT3 activation. Biochem. Biophys. Res. Commun. 425, 304-308. <https://doi.org/10.1016/j.bbrc.2012.07.086>
17. Silva, F. M., de Almeida, J. C., Feoli, A. M. (2011) Effect of diet on adiponectin levels in blood. Nutr. Rev. 69, 599-612. <https://doi.org/10.1111/j.1753-4887.2011.00414.x>
18. Singh, S., Akhtar, N., Ahmad, J. (2012) Plasma adiponectin levels in women with polycystic ovary syndrome: impact of Metformin treatment in a case­control study. Diabetes Metab. Syndr. 6, 207-211. <https://doi.org/10.1016/j.dsx.2012.05.013>
19. Tan, B. K., Adya, R., Farhatullah, S., Lewandowski, K. C., O’Hare, P., Lehnert, H., Randeva, H. S. (2008) Omentin-1, a novel adipokine, is decreased in overweight insulin­resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin­1 by insulin and glucose. Diabetes 57, 801-808. <https://doi.org/10.2337/db07-0990>
20. Tan, B. K., Adya, R., Farhatullah, S., Chen, J., Lehnert, H., Randeva, H. S. (2010) Metformin treatment may increase omentin­1 levels in women with polycystic ovary syndrome. Diabetes 59, 3023-3031. <https://doi.org/10.2337/db10-0124>
21. Verzegnassi, F., Chinello, M. (2010) Exenatide in type 2 diabetes. Lancet 376, 1052-1053. <https://doi.org/10.1016/S0140-6736(10)61485-7>
22. Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R., L., Ferrante, A., W. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112, 1796–1808. <https://doi.org/10.1172/JCI200319246>
23. Xu, D., Huang, X. D., Yuan, J., P., Wu, J., Fan, Y., Luo, H. S., Yang, Y. H. (2011) Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in NAFLD. Hepatogastroenterology 58, 1703-1707.
24. Yan, P., Liu, D., Long, M., Ren, Y., Pang, J., Li, R. (2011a) Changes of serum omentin levels and relationship between omentin and adiponectin concentrations in type 2 diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 119, 257-263. <https://doi.org/10.1055/s-0030-1269912>
25. Yan, P., Li, L., Yang, M., Liu, D., Liu, H., Boden, G., Yang, G. (2011b) Effects of the long-acting human glucagon-like peptide­1 analog liraglutide on plasma omentin­1 levels in patients with type 2 diabetes mellitus. Diabetes Res. Clin. Pract. 92, 368-374. <https://doi.org/10.1016/j.diabres.2011.02.030>
26. Yang, R. Z., Lee, M. J., Hu, H., Pray, J., Wu, H. B., Hansen, B. C., Shuldiner, A. R., Fried, S. K., McLenithan, J. C., Gong, D.W. (2006) Identification of omentin as a novel depot- specific adipokine in human adipose tissue: possible role in modulating insulin action. Am. J. Physiol. Endocrinol. Metab. 290, E1253-1261. <https://doi.org/10.1152/ajpendo.00572.2004>
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive