Fol. Biol. 2015, 61, 81-89
https://doi.org/10.14712/fb2015061020081
Curcumin-Mediated Reversal of p15 Gene Promoter Methylation: Implication in Anti-Neoplastic Action against Acute Lymphoid Leukaemia Cell Line
References
1. 2003) Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 23, 363-398.
, B. B., Kumar, A., Bharti, A. C. (
2. 2013) Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives. Curr. Pharm. Des. 19, 578-613.
< , F., Barbosa, A. J., Parenti, M. D., Del Rio, A. (https://doi.org/10.2174/138161213804581918>
3. 1999) Modulatory effects of curcumin on the chromosomal damage induced by doxorubicin in Chinese hamster ovary cells. Teratog. Carcinog. Mutagen. 19, 1-8.
< , L. M., Araújo, M. C., Dias, F. L., Takahashi, C. S. (https://doi.org/10.1002/(SICI)1520-6866(1999)19:1<1::AID-TCM1>3.0.CO;2-7>
4. 1999) p15INK4B CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing. Blood 94, 2445-2451.
< , E. E., Baylin, S. B., Herman, J. G. (https://doi.org/10.1182/blood.V94.7.2445.419k19_2445_2451>
5. 2009) Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 106, 13433-13438.
< , S. S., Raval, A., Johnson A. J., Hertlein, E., Liu, T. H., Jin, V. X. (https://doi.org/10.1073/pnas.0906455106>
6. 2003) Epigenetic inactivation of INK4/CDK/RB cell cycle pathway in acute leukemias. Ann. Hematol. 82, 738-742.
< , C. S., Wong, A. S., Kwong, Y. L. (https://doi.org/10.1007/s00277-003-0744-8>
7. 2002) 5-Azacytidine and 5-aza-2’-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 21, 5483-5495.
< , J. (https://doi.org/10.1038/sj.onc.1205699>
8. 1994) A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal. Biochem. 218, 314-319.
< , J., Traganos, F., Darzynkiewicz, Z. (https://doi.org/10.1006/abio.1994.1184>
9. 1998) Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb. Leukemia 12, 1266-1271.
< , K., Nedergaard, T., Andersen, M. K., thor Straten, P., Guldberg, P., Møller, P., Zeuthen, J., Ebbe Hansen, N., Hou-Jensen, K., Ralfkiaer, E. (https://doi.org/10.1038/sj.leu.2401090>
10. 1999) Different effects of photodynamic therapy and γ-irradiation on vascular smooth muscle cells and matrix: implications for inhibiting restenosis. Arterioscler. Thromb. Vasc. Biol. 19, 2154-2161.
< , J., Leszczynski, D., Schiereck, J., Kung, J., LaMuraglia, G. M. (https://doi.org/10.1161/01.ATV.19.9.2154>
11. 1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA 93, 9821-9826.
< , J. G., Graff, J. R., Myohanen, S., Nelkin, B. D., Baylin, S. B. (https://doi.org/10.1073/pnas.93.18.9821>
12. 1997) Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of haematological malignancies. Cancer Res. 57, 837-841.
, J. G., Civin, C. I., Issa, J. P., Collector, M. I., Sharkis, S. J., Baylin, S. B. (
13. 2002) Staphylococcus aureus agr and sara functions are required for invasive infection but not inflammatory responses in the lung. Infect. Immun. 70, 127-133.
< , G., Saba, S., Adamo, R., Rush, W., Soong, G., Cheung, A., Prince, A. (https://doi.org/10.1128/IAI.70.1.127-133.2002>
14. 2010) Reversal of hypermethylation and reactivation of the RARβ2 gene by natural compounds in cervical cancer cell lines. Folia Biol. (Praha) 56, 195-200.
, A. K., Nikbakht, M., Parashar, G., Shrivastava, A., Capalash, N., Kaur J. (
15. 1975) Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J. Cell. Biol. 66, 188-193.
< , A. (https://doi.org/10.1083/jcb.66.1.188>
16. 2005) Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol. Pharmacol. 68, 1018-1030.
< , W. J., Shim, J. Y., Zhu, B. T. (https://doi.org/10.1124/mol.104.008367>
17. 2006) Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells. J. Biol. Chem. 281, 10118-10126.
< , A., De Plaen, E., Boon, T., De Smet, C. (https://doi.org/10.1074/jbc.M510469200>
18. 1998) Increased DNA methyltransferase expression in leukaemia. Leukemia 12, 311-316.
< , J. R., Warnecke, P., Vincent, P. C., Clark, S. J. (https://doi.org/10.1038/sj.leu.2400932>
19. 2010) DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma. Clin. Cancer Res. 16, 2751-2759.
< , K., Chano, T., Kawakami, T. (https://doi.org/10.1158/1078-0432.CCR-09-3338>
20. 2001) Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 97, 1172-1179.
< , S., Chijiwa, T., Okamura, T., Akashi, K., Fukumaki, Y., Niho, Y. (https://doi.org/10.1182/blood.V97.5.1172>
21. 2005). Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage. Br. J. Haematol. 129, 189-198.
< , J., Frost, B. M., Forestier, E., Gustafsson, G., Nygren, P., Hellebostad, M., Jonsson, O. G., Kanerva, J., Schmiegelow, K., Larsson, R., Lönnerholm, G., (https://doi.org/10.1111/j.1365-2141.2005.05433.x>
22. 2011) Epigenetic changes induced by curcumin and other natural compounds. Genes Nutr. 6, 93-108.
< , S., Gupta, S. C., Park, B., Goel, A., Aggarwal, B. B. (https://doi.org/10.1007/s12263-011-0222-1>
23. 2010) Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. J. Pharmacol. Exp. Ther. 335, 114-123.
< , Y., Simo, G. P., Calvin, E., Blas, E. D., Aller, P. (https://doi.org/10.1124/jpet.110.168344>
24. 2000) Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5, 415-418.
< , H. U., Haj-Yehia, A., Levi-Schaffer, F. (https://doi.org/10.1023/A:1009616228304>
25. 1995) Genomic structure, expression and mutational analysis of the P15 (MTS2) gene. Oncogene 11, 987-991.
, S., Dayananth, P., Jiang, P., Weaver-Feldhaus, J. M., Tavtigian, S. V., Cannon-Albright, L. (
26. 2005) Anticancer effect of curcumin on human B cell non-Hodgkin’s lymphoma. J. Huazhong Univ. Sci. Technolog. Med. Sci. 25, 404-407.
, C., Liu, X., Chen, Y., Liu, F (
27. 2001) DNA methylation: an alternative pathway to cancer. Ann. Surg. 234, 10-20.
< , S. A., Laird, P. W., De Meester, T. R. (https://doi.org/10.1097/00000658-200107000-00003>
28. 1998) Transcriptional silencing of the p16 gene in human myeloma-derived cell lines by hypermethylation. Br. J. Haematol. 103, 168-175.
, I. H., Ng, M. H., Lee, J. C., Lo, K. W., Chung, Y. F., Huang, D. P. (
29. 2000) Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients. Clin. Cancer Res. 6, 3516-3521.
, I. H., Lo, Y. M., Yeo, W., Lau, W. Y., Johnson, P. J. (
30. 2013) Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS One 8, e55934.
< , J., Peng, Y., Wu, L. C., Xie, Z., Deng, Y., Hughes, T., He, S., Mo, X. K., Chiu, M., Wang, Q. E., He, X., Shujun Liu, S., Grever, M. R., Liu, Z. (https://doi.org/10.1371/journal.pone.0055934>
31. 1998) Frequent deletion and 5’CpG island methylation of the p16 gene in primary malignant lymphoma of the brain. Cancer Res. 58, 1231-1237.
, S. J., Endo, S., Ichikawa, T., Washiyama, K., Kumanishi, T (
32. 2007) Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA. Clin. Cancer Res. 13, 2378-2384.
< , Y. J., Wu, H. C., Shen, J., Ahsan, H., Tsai, W. Y., Yang, H. I. (https://doi.org/10.1158/1078-0432.CCR-06-1900>
33. 2009) Curcumin is a potent DNA hypomethylation agent. Bioorg. Med. Chem. Lett. 19, 706-709.
, L, Zhiliang, X., William, J., Ryan, E. P., Shujun, L., Jianhua, Y., Pui-kai, L., Jiayuh, L., Jame, R. F., Marcucci, G. M., Chenglong, L., Chan, K. K. (
34. 2000) Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia. Blood 96, 2879-2886.
, C. M., Kaspers, G. J., Pieters, R., Ramakers-Van Woerden, N. L, den Boer, M. L., Wünsche, R., Rottier, M. M., Hählen, K., van Wering, E. R., Janka-Schaub, G. E., Creutzig, U., Veerman, A. J. (