Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

Crossref logo

Fol. Biol. 2015, 61, 241-246

https://doi.org/10.14712/fb2015061060241

Immune Function Alterations during 12 Weeks of Abstinence in Heroin Users

Z. Wang1, X-R. Yang1, H. Song1, B-R. Cao1, F. Yin2, Z-M. An1, Lin Kang1, Jing Li1

1West China Hospital, Si Chuan University, Cheng Du, Si Chuan, China
2West China School of Public Health, Si Chuan University, Cheng Du, Si Chuan, China

Received April 2015
Accepted October 2015

References

1. Bosch, J. A., Brand, H. S., Ligtenberg, A. J. M., Hoogstraten, J., Nieuw Amerongen, A. V. (1998) The response of salivary protein levels and S-IgA to an academic examination are associated with daily stress. J. Psychophysiol. 12, 384-391.
2. Chan, Y. Y., Yang, S. N., Lin, J. C., Chang, J. L., Lin, J. G., Lo, W. Y. (2015) Inflammatory response in heroin addicts undergoing methadone maintenance treatment. Psychiatry Res. 226, 230-234. <https://doi.org/10.1016/j.psychres.2014.12.053>
3. Charlton, B., Lafferty, K. J. (1994) The Th1/Th2 balance in autoimmunity. Curr. Op. Immunol. 7, 793-798. <https://doi.org/10.1016/0952-7915(95)80050-6>
4. Crowe, A. V., Howse, M., Bell, G. M., Henry, J. A. (2000) Substance abuse and the kidney. Q. J. Med. 93, 147-152. <https://doi.org/10.1093/qjmed/93.3.147>
5. Deinzer, R., Schuller, N. (1998) Dynamics of stress-related decrease of salivary immunoglobulin A (sIgA): relationship to symptoms of the common cold and studying behavior. Behav. Med. 23, 161-169. <https://doi.org/10.1080/08964289809596372>
6. Dobbin, J. P., Harth, M., McCain, G. A. (1991) Cytokine production and lymphocyte transformation during stress. Brain Behav. Immun. 5, 339-348. <https://doi.org/10.1016/0889-1591(91)90029-A>
7. Doherty, M. C., Garfein, R. S., Monterroso, E., Brown, D., Vlahov, D. (2000) Correlates of HIV infection among young adult short-term injection drug users. AIDS 14, 717-726. <https://doi.org/10.1097/00002030-200004140-00011>
8. Dooley, D., Vidal, P., Hendrix, S. (2014) Immunopharmacological intervention for successful neural stem cell therapy: new perspectives in CNS neurogenesis and repair. Pharmacol. Ther. 141, 21-31. <https://doi.org/10.1016/j.pharmthera.2013.08.001>
9. Eisenstein, T. K., Hilburger, M. E. (1998) Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations. J. Neuroimmunol. 83, 36-44. <https://doi.org/10.1016/S0165-5728(97)00219-1>
10. Fawzy, F. I. (1995) Behavior and immunity. In: Comprehensive Textbook of Psychiatry, eds. Kaplan, H. I., Sodock, B. J., pp. 1559-1570, Williams & Wilkins, Baltimore.
11. Fecho, K., Maslonek, K. A., Dykstra, L. A., Lysle, D. T. (1996) Evidence for sympathetic and adrenal involvement in the immunomodulatory effects of acute morphine treatment in rats. J. Pharmacol. Exp. Ther. 277, 633-645.
12. Glaser, R., Rice, J., Speicher, C. E. (1986) Stress depresses interferon production and natural killer (NK) cell activity in humans. Behav. Neurosci. 100, 675-678. <https://doi.org/10.1037/0735-7044.100.5.675>
13. Glaser, R., Rice, J., Sheridan, J. (1987) Stress-related immune suppression: health implications. Brain Behav. Immun. 1, 7-20. <https://doi.org/10.1016/0889-1591(87)90002-X>
14. Glaser, R., Kennedy, S., Lafuse, W. P., Bonneau, R. H., Speicher, C., Hillhouse, J., Kiecolt Glaser, J. K. (1990) Psychological stress-induced modulation of interleukin-2 receptor gene expression and interleukin-2 production in peripheral blood leukocytes. Arch. Gen. Psychiatry 47, 702-712. <https://doi.org/10.1001/archpsyc.1990.01810200015002>
15. Glaser, R., Pearson, G. R., Jones, J. F., Hillhouse, J., Kennedy, S., Mao H. Y., Kiecolt Glaser, J. K. (1991) Stress-related activation of Epstein-Barr virus. Brain Behav. Immun. 5, 219-232. <https://doi.org/10.1016/0889-1591(91)90018-6>
16. Kang, D., Coe, C. L., McCarthy, D. O. (1996) Academic examinations significantly impact immune responses, but not lung function, in healthy and well-managed asthmatic adolescents. Brain Behav. Immun. 10, 164-181. <https://doi.org/10.1006/brbi.1996.0015>
17. Koh, K. B. (2001) The relationship of stress-induced hypothalamic- pituitary-adrenal axis function with cell-mediated immunity. J. Korean Neuropsychiatr. Assoc. 40, 857-866.
18. Koh, K. B., Choe, E., Song, J. E., Lee, E. H. (2006) Effect of coping on endocrinoimmune functions in different stress situations. Psychiatry Res. 143, 223-234. <https://doi.org/10.1016/j.psychres.2005.04.008>
19. Lees, J. R., Golumbek, P. T., Sim, J., Dorsey, D., Russell, J. H. (2008) Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis. J. Exp. Med. 205, 2633-2642. <https://doi.org/10.1084/jem.20080155>
20. Leguit, Jr. P., Slot, H., Roos, C. (1982) The ‘acute’ abdomen in heroin addiction. Br. J. Surg. 69, 598. <https://doi.org/10.1002/bjs.1800691014>
21. Liesz, A., Suri-Payer, E., Veltkamp, C., Doerr, H., Sommer, C., Rivest, S. (2009) Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat. Med. 15, 192-199. <https://doi.org/10.1038/nm.1927>
22. Marchesi, G. F., Cotani, P., Santone, G. (1989) Psychological and immunological relationships during acute academic stress. New Trends Exp. Clin. Psychiatry 5, 5-22.
23. Martin, J. L., Koodie, L., Krishinam, A. G.., Charboneau, R., Barke, R. A., Roy, S. (2010) Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site. Am. J. Pathol. 176, 786-800. <https://doi.org/10.2353/ajpath.2010.090457>
24. Marucha, P. T., Kiecolt-Glaser, J. K., Favagehi, M. (1998) Mucosal wound healing is impaired by examination stress. Psychosom. Med. 60, 362-365. <https://doi.org/10.1097/00006842-199805000-00025>
25. McCarthy, L., Wetzel, M., Sliker, J. K., Eisenstein, T. K., Rogers, T. J. (2001) Opioids, opioid receptors, and the immune response. Drug Alcohol Depend. 62, 111-123. <https://doi.org/10.1016/S0376-8716(00)00181-2>
26. Mosman, T. R., Sad, S. (1996) The expanding universe of T-cell subsets; Th1, Th2 and more. Immunol. Today 17, 138-146. <https://doi.org/10.1016/0167-5699(96)80606-2>
27. Nelson, C. J., Schneider, G. M., Lysle, D. T. (2000) Involvement of central μ- but not δ- or κ-opioid receptors in immunomodulation. Brain Behav. Immun. 14, 170-184. <https://doi.org/10.1006/brbi.1999.0575>
28. Nikolova, M., Ljubomirova, M., Iliev, A., Krasteva, R., Andreev, E., Radenkova, J. (2002) Clinical significance of antinuclear antibodies, antineutrophil cytoplasmic antibodies and anticardiolipin antibodies in heroin abusers. IMAJ 4(Suppl 11), 908-910.
29. Pacifici, R., diCarlo, S., Bacosi, A., Pichini, S., Zuccaro, P. (2000) Pharmacokinetics and cytokine production in heroin and morphine-treated mice. Int. J. Immunopharmacol. 22, 603-614. <https://doi.org/10.1016/S0192-0561(00)00023-0>
30. Peterson, P. K., Molitor, T. W., Chao, C. C. (1993) Mechanisms of morphine-induced immunomodulation. Biochem. Pharmacol. 46, 343-348. <https://doi.org/10.1016/0006-2952(93)90508-T>
31. Peterson, P. K., Molitor, T. W., Chao, C. C. (1998) The opioidcytokine connection. J. Neuroimmunol. 83, 63-69. <https://doi.org/10.1016/S0165-5728(97)00222-1>
32. Pier, G. B., Lyczak, J. B., Wetzler, L. M. (2004) Immunology, Infection, and Immunity. ASM Press, Washington.
33. Romagnani, S. (1994) Lymphokine production by human T cell in disease states. Annu. Rev. Immunol. 12, 227-257. <https://doi.org/10.1146/annurev.iy.12.040194.001303>
34. Rojas, I. G., Padgett, D. A., Sheridan, J. F., Marucha, P. T. (2002) Stress-induced susceptibility to bacterial infection during cutaneous wound healing. Brain Behav. Immun. 16, 74-84. <https://doi.org/10.1006/brbi.2000.0619>
35. Sarder, M., Abe, K., Saito, H., Nishiyama, N. (1996) Comparative effect of IL-2 and IL-6 on morphology of cultured hippocampal neurons from fetal rat brain. Brain Res. 715, 9-16. <https://doi.org/10.1016/0006-8993(95)01291-5>
36. Savona, S., Nardi, M. A., Lennete, E. T., Karpatkin, S. (1985) Thrombocytopenic purpura in narcotic addicts. Ann. Intern. Med. 102, 737-41. <https://doi.org/10.7326/0003-4819-102-6-737>
37. Schmitz, T., Chew, L. J. (2008) Cytokines and myelination in the central nervous system. ScientificWorldJournal 8, 1119-1147. <https://doi.org/10.1100/tsw.2008.140>
38. Simonovska, N., Chibishev, A., Bozinovska, C, Grcevska, L., Dimitrovski, K., Neceva, V. (2011) Evaluation of circulating immune complexes and antiphospholipid antibodies (anti β 2 glycoprotein 1) in heroin addicts and their clinical significance. Med. Arh. 65, 324-326. <https://doi.org/10.5455/medarh.2011.65.324-326>
39. Stefano, G. B., Scharrer, B., Smith, E. M., Hughes, Jr. T. K., Magazine, H. I., Bilfinger, T. V., Hartman, A. R., Fricchione, G. L., Liu, Y., Makman, M. H. (1996) Opioid and opiate immunoregulatory processes. Crit. Rev. Immunol. 16, 109-144. <https://doi.org/10.1615/CritRevImmunol.v16.i2.10>
40. Tennant, F. (2001) Hepatitis C, B, D, and A: contrasting features and liver function abnormalities in heroin addicts. J. Addict. Dis. 20, 9-17. <https://doi.org/10.1300/J069v20n01_02>
41. Wang, G., Lu, C., Liu, H., Jin, W., Jiao, X., Wei, G., Chen, J., Zhu, Y. (2001) Immunohistochemical localization of interleukin- 2 and its receptor subunits α, β and γ in the main olfactory bulb of the rat. Brain Res. 893, 244-252. <https://doi.org/10.1016/S0006-8993(00)03317-5>
42. Weber, R. J., Gomez-Flores, R., Smith, J. E., Martin, T. J. (2004) Immune, neuroendocrine, and somatic alterations in animal models of human heroin abuse. J. Neuroimmunol. 147, 134-137. <https://doi.org/10.1016/j.jneuroim.2003.10.029>
43. Weiss, J. M., Sundar, S. (1992) Effects of stress on cellular immune responses in animals. In: American Psychiatric Press Review of Psychiatry, eds. Tasman, A., Riba, M. B., pp. 127-144, American Psychiatric Press, Washington.
44. Zajícová, A., Wilczek, H., Holáň, V. (2004) The alterations of immunological reactivity in heroin addicts and their normalization in patients maintained on methadone. Folia Biol. (Praha) 50, 24-28.
45. Zaki, N. G., Osman, A., Moustafa, H., Saad, A. H. (2006) Alterations of immune functions in heroin addicts. Egypt J. Immunol. 13, 153-71.
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive