Fol. Biol. 2016, 62, 34-39

https://doi.org/10.14712/fb2016062010034

The Impact of 4-Nonylphenol on the Viability and Hormone Production of Mouse Leydig Cells

T. Jambor1, J. Lukáčová1, E. Tvrdá1, Z. Kňažická1, Z. Forgács2, Norbert Lukáč1

1Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Slovak Republic
2National Institute of Chemical Safety, Budapest, Hungary

Received April 2015
Accepted January 2016

References

1. Berryman, D., Houde, F., Deblois, C., O’Shea, M. (2004) Nonylphenolic compound in drinking and surface waters downstream of treated textile and pulp and paper effluents: a survey and preliminary assessment of their potential effects on public health in aquatic life. Chemosphere 56, 247-255. <https://doi.org/10.1016/j.chemosphere.2004.02.030>
2. Chapin, R. E., Delaney, J., Wang, Y., Lanning, L., Davis, B., Collins, B. (1999) The effect of 4-nonylphenol in rats: a multigeneration reproduction study. Toxicol. Sci. 52, 80-91. <https://doi.org/10.1093/toxsci/52.1.80>
3. Gong, Y. I., Han, X. D. (2006) Effect of nonylphenol on steroidogenesis of rat Leydig cells. J. Environ. Sci. Heal. B. 41, 705-715. <https://doi.org/10.1080/03601230600701866>
4. Han, X. D., Tu, Z. G., Gong, Y., Shen, S. N., Wang, X. Y., Kang, L. N., Hou, Y. Y., Chen, J. X. (2004) The toxic effects of nonylphenol on the reproductive system of male rats. Reprod. Toxicol. 19, 215-221. <https://doi.org/10.1016/j.reprotox.2004.06.014>
5. Chapin, R. E., Delaney, J., Wang, Y., Lanning, L., Davis, B., Collins, B. (1999) The effect of 4-nonylphenol in rats: a multigeneration reproduction study. Toxicol. Sci. 52, 80-91. <https://doi.org/10.1093/toxsci/52.1.80>
6. Jambor, T., Lukáčová, J., Tvrdá, E., Kńažická, Z., Forgács, Z., Lukáč, N. (2015) Impact of 4-nonylphenol on testosterone production in mice Leydig cells. J. Microbiol. Biotech. Food Sci. 4, 42-44. <https://doi.org/10.15414/jmbfs.2015.4.special2.42-44>
7. Langford, K. H., Lester, J. N. (2002) Fate and behavior of endocrine disrupters in wastewater treatment processes, In: Endocrine Disrupters in Wastewater and Sludge Treatment Processes, eds. Brikett, J. W., Lester, J. N. CRC Press, Boca Raton, FL
8. Laurenza, E. M., Balasubramanian, G., Weis, C., Blaydes, B., Newbold, R. R., Delclos, K. B. (2002) Effect of nonylphenol on serum testosterone levels and testicular steroidogenic enzyme activity in neonatal, pubertal, and adult rats. Chem. Biol. Interact. 139, 23-41. <https://doi.org/10.1016/S0009-2797(01)00291-5>
9. Lavoie, H. A., King, S. R. (2009) Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B. Exp. Biol. Med. 234, 880-907. <https://doi.org/10.3181/0903-MR-97>
10. Lee, P. C., Arndt, P., Nickels, K. C. (1999) Testicular abnormalities in male rats after lactational exposure to nonylphenols. Endocrine 11, 61-68. <https://doi.org/10.1385/ENDO:11:1:61>
11. Murono, E. P., Derk, R. C., De León, J. H., (1999) Biphasic effects of octylphenol on testosterone biosynthesis by cultured Leydig cells from neonatal rats. Reprod. Toxicol 13, 451-462. <https://doi.org/10.1016/S0890-6238(99)00047-7>
12. Mendis-Handagama, S. M., Ariyaratne, H. B. (2001) Differentiation of the adult Leydig cell population in the postnatal testis. Biol. Reprod. 65, 660-671. <https://doi.org/10.1095/biolreprod65.3.660>
13. Payne, A. H., Sha, L. (1991) Multiple mechanisms for regulation of 3β-hydroxysteroid dehydogenase/Δ5→Δ4-isomerase, 17α-hydroxylase/C17–20 lyase cytochrome P450, and cholesterol side-chain cleavage cytochrome P450 messenger ribonucleic acid levels in primary cultures of mouse Leydig cells. Endocrinology 129, 1429-1435. <https://doi.org/10.1210/endo-129-3-1429>
14. Sanderson, T. J. (2006) The steroid hormone biosynthesis pathway as a target for endocrine disrupting chemicals. Toxicol. Sci. 94, 3-21. <https://doi.org/10.1093/toxsci/kfl051>
15. Soares, A., Guieysse, B., Jefferson, B., Cartmell, E., Lester, J. (2008) Nonylphenol in the environment: a critical review on occurrence, fate, toxicity and treatment in wastewaters. Environ. Int. 34, 1033-1049. <https://doi.org/10.1016/j.envint.2008.01.004>
16. Stoklosowa, S. (1982) Tissue culture of gonadal cells. Acta Biol. Acad. Sci. Hung. 33, 367-379.
17. Svechnikov, K., Izzo, G., Landreh, L., Weisser, J., Söder, O. (2010) Endocrine disruptors and Leydig cell function. J. Biomed. Biotechnol. 2010, 1-11. <https://doi.org/10.1155/2010/684504>
18. Thoreux-Manlay, A., Le Goascogne, C., Segretain, D., Jegou, B., Pinon-Lataillade, G. (1995) Lead affects steroidogenesis in rat Leydig cells in vivo and in vitro. Toxicology 103, 53-62. <https://doi.org/10.1016/0300-483X(95)03107-Q>
19. Wu, J. J., Wang, K. L., Wang, S. W., Hwang, I. M., Chen, M. L., Wang, P. S. (2010) Differential effects of nonylphenol on testosterone secretion in rat Leydig cells. Toxicology 268, 1-7. <https://doi.org/10.1016/j.tox.2009.10.030>
20. Yao, G., Ling, L., Luan, J., Ye, D., Zhu, P. (2007) Nonylphenol induces apoptosis of Jurkat cells by a caspase-8 dependent mechanism. Int. Imunopharmacol. 7, 444-453. <https://doi.org/10.1016/j.intimp.2006.11.013>
21. Ying, F., Ding, C., Ge, R., Wang, X., Li, F., Zhang, Y., Zeng, Q., Yu, B., Ji, R., Han, X. (2012) Comparative evaluation of nonylphenol isomers on steroidogenesis of rat Leydig cells. Toxicol. In Vitro 26, 1114-1121. <https://doi.org/10.1016/j.tiv.2012.06.016>
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive