Fol. Biol. 2018, 64, 59-64

https://doi.org/10.14712/fb2018064020059

Nos3 Gene Rs1799983 and Rs2070744 Polymorphisms in Patients with Periodontal Disease

M. Mazurek-Mochol1, M. Kozak2, M. Sawczuk3, A. Maciejewska3, D. Malinowski4, K. Safranow5, Andrzej Pawlik6

1Department of Periodontology, Pomeranian Medical University, Szczecin, Poland
2Department of Prosthetics, Pomeranian Medical University, Szczecin, Poland
3Department Faculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland
4Department of Pharmacology, Pomeranian Medical University, Szczecin, Poland
5Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
6Department of Physiology, Pomeranian Medical University, Szczecin, Poland

Received January 2018
Accepted May 2018

References

1. American Academy of Periodontology Task Force Report on the Update to the 1999 Classification of Periodontal Diseases and Conditions (2015) J. Periodontol. 86, 835-838.
2. Dosenko, V. I., Zahorii, V., Moibenko, O. O. (2006) Proteasomal degradation of ribonucleic acids of different NO-synthase isoforms. Fiziol. Zh. 52, 3-7.
3. Eley, B. M., Cox, S. W. (2003) Proteolytic and hydrolytic enzymes from putative periodontal pathogens: characterization, molecular genetics, effects on host defenses and tissues and detection in gingival crevice fluid. Periodontol. 2000 31, 105-124. <https://doi.org/10.1034/j.1600-0757.2003.03107.x>
4. Graves, D., Cochran, D. (2003) The contribution of interleukin- 1 and tumor necrosis factor to periodontal tissue destruction. J. Periodontol. 74, 391-401. <https://doi.org/10.1902/jop.2003.74.3.391>
5. Hoyt, J. C., Robbins, R. A., Habib, M., Springall, D. R., Buttery, L. D., Polak, J. M., Barnes, P. J. (2003) Cigarette smoke decreases inducible nitric oxide synthase in lung epithelial cells. Exp. Lung Res. 29, 17-28. <https://doi.org/10.1080/01902140303759>
6. Hussain, Q. A., McKay, I. J., Gonzales-Marin, C., Allaker, R. P. (2016) Detection of adrenomedullin and nitric oxide in different forms of periodontal disease. J. Periodontal. Res. 51, 16-25. <https://doi.org/10.1111/jre.12273>
7. Johnson, G. K., Guthmiller, J. M. (2007) The impact of cigarette smoking on periodontal disease and treatment. Periodontol. 2000 44, 178-194. <https://doi.org/10.1111/j.1600-0757.2007.00212.x>
8. Jung, H., Kim, Y., Park, J., Suh, J., Lee, J. (2013) The expression of a nitric oxide derivative, tissue inhibitors of metalloproteinase-3, and tissue inhibitors of metalloproteinase-4 in chronic periodontitis with type 2 diabetes mellitus. J. Periodontal. Implant. Sci. 43, 87-95. <https://doi.org/10.5051/jpis.2013.43.2.87>
9. Lefer, A. M. (1997) Nitric oxide: nature’s naturally occurring leukocyte inhibitor. Circulation 95, 553-554. <https://doi.org/10.1161/01.CIR.95.3.553>
10. Lohinai, Z., Benedek, P., Fehér, E., Györfi, A., Rosivall, L., Fazekas, A., Salzman, A. L., Szabó, C. (1998) Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat. Br. J. Pharmacol. 123, 353-360. <https://doi.org/10.1038/sj.bjp.0701604>
11. Lucarini, G., Tirabassi, G., Zizzi, A., Balercia, G., Quaranta, A., Rubini, C., Aspriello, S. D. (2016) Uncoupling of vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (iNOS) in gingival tissue of type 2 diabetic patients. Inflammation 39, 632-642. <https://doi.org/10.1007/s10753-015-0288-9>
12. Nebel, D., Arvidsson, J., Lillqvist, J., Holm, A., Nilsson, B. O. (2013) Differential effects of LPS from Escherichia coli and Porphyromonas gingivalis on IL-6 production in human periodontal ligament cells. Acta Odontol. Scand. 71, 892-898. <https://doi.org/10.3109/00016357.2012.734415>
13. Nishikawa, T., Naruse, K., Kobayashi, Y., Miyajima, S., Mizutani, M., Kikuchi, T., Soboku, K., Nakamura, N., Sokabe, A., Tosaki, T., Hata, M., Ohno, N., Noguchi, T., Matsubara, T. (2012) Involvement of nitrosative stress in experimental periodontitis in diabetic rats. J. Clin. Periodontol. 39, 342-349. <https://doi.org/10.1111/j.1600-051X.2011.01848.x>
14. Otenio, C. C., Fonseca, I., Martins, M. F., Ribeiro, L. C., Assis, N. M., Ferreira, A. P., Ribeiro, R. A. (2012) Expression of IL-1, IL-6, TNF-α, and iNOS in pregnant women with periodontal disease. Genet. Mol. Res. 11, 4468-4478. <https://doi.org/10.4238/2012.September.20.3>
15. Özdemir, B., Özmeric, N., Elgün, S., Barış, E. (2016) Smoking and gingivitis: focus on inducible nitric oxide synthase, nitric oxide and basic fibroblast growth factor. J. Periodontal. Res. 51, 596-603. <https://doi.org/10.1111/jre.12338>
16. Ozer, L., Elgun, S., Ozdemir, B., Pervane, B., Ozmeric, N. (2011) Arginine-nitric oxide-polyamine metabolism in periodontal disease. J. Periodontol. 82, 320-328. <https://doi.org/10.1902/jop.2010.100199>
17. Pan, Z., Guzeldemir, E., Toygar, H. U., Bal, N., Bulut, S. (2010) Nitric oxide synthase in gingival tissues of patients with chronic periodontitis and with and without diabetes. J. Periodontol. 81, 109-120. <https://doi.org/10.1902/jop.2009.090454>
18. Preshaw, P. M., Taylor, J. J. (2011) How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis? J. Clin. Periodontol. 38, 60-84. <https://doi.org/10.1111/j.1600-051X.2010.01671.x>
19. Shaker, O., Ghallab, N. A., Hamdy, E., Sayed, S. (2013) Inducible nitric oxide synthase (iNOS) in gingival tissues of chronic periodontitis with and without diabetes: immunohistochemistry and RT-PCR study. Arch. Oral. Biol. 58, 1397-1406. <https://doi.org/10.1016/j.archoralbio.2013.05.003>
20. Shin, S., Kim, Y. S., Lee, S. Y., Bae, W. J., Park, Y. D., Hyun, Y. C., Kang, K., Kim, E. C. (2015) Expression of phospholipase D in periodontitis and its role in the inflammatory and osteoclastic response by nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells. J. Periodontol. 86, 1405-1416. <https://doi.org/10.1902/jop.2015.150123>
21. Stefanovic-Racic, M., Stadler, J., Evans, C. H. (1993) Nitric oxide and arthritis. Arthritis. Rheum. 36, 1036-1044. <https://doi.org/10.1002/art.1780360803>
22. Wang, J., Dudley, D., Wang, X. L. (2002) Haplotype-specific effects on endothelial NO synthase promoter efficiency: modifiable by cigarette smoking. Arterioscler. Thromb. Vasc. Biol. 22, e1-4.
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Archive