Exendin-4 Induces Cytotoxic Autophagy in Two Ovarian Cancer Cell Lines through Inhibition of Mtorc1 Mediated by Activation of AMPK and Suppression of Akt Cited by

Fol. Biol. 2020, 66, 186-203

https://doi.org/10.14712/fb2020066050186

Exendin-4 Induces Cytotoxic Autophagy in Two Ovarian Cancer Cell Lines through Inhibition of Mtorc1 Mediated by Activation of AMPK and Suppression of Akt

Rehab M. Badi^1,2, E. F. Khaleel^1,3, M. H. El-Bidawy^3,4, H. H. Satti^5,6, D. G. Mostafa^1,7

¹Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia
²Department of Physiology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan
³Department of Medical Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt
⁴Department of BMS, Division of Physiology, College of Medicine, Prince Sattam Ibn Abdulaziz University, Al-Kharj, Saudi Arabia
⁵Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia
⁶Department of Pathology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan
⁷Department of Medical Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt

Received May 18, 2020
Accepted October 20, 2020

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