Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

Crossref logo

Fol. Biol. 2021, 67, 108-117

https://doi.org/10.14712/fb2021067030108

Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma

B. F. Yan1,2, X. Chen3, J. Liu2, S. J. Liu1, J. Z. Zhang2, Qingqi Zeng2, J. A. Duan1

1Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, and Key Laboratory of Chinese Medicinal Resources Recycling Utilization, State Administration of Traditional Chinese Medicine, Nanjing University of Chinese Medicine; Nanjing, China
2Jiangsu Health Vocational College; Nanjing, China
3Jiangsu College of Nursing; Huaian, China

Received May 2021
Accepted June 2021

Crossref Cited-by Linking

  • Chen Rong, Zhang Wan, Zhang Meizhi, Liu Weidong, Feng Weike, Zhang Yanan: Asiatic acid in anticancer effects: emerging roles and mechanisms. Front. Pharmacol. 2025, 16. <https://doi.org/10.3389/fphar.2025.1545654>
  • Li Huizhen, Fang Guixuan, Tian Wen, Liao Yinglin, Xiang Jing, Hu Yingying, Luo Lianxiang: Asiatic acid induces lung cancer toxicity by triggering SRC-mediated ferroptosis. Toxicology and Applied Pharmacology 2024, 492, 117097. <https://doi.org/10.1016/j.taap.2024.117097>
  • Wang Ru, Yang Bo, Zhang Beibei, Zhang Qinqin, Cao Bing, Jia Jufang, Liu Meng, Guo Pengli, Zhang Yuhan, Li Xiaokun, Zheng Xiaoke, Feng Weisheng: A new amide alkaloid induces the apoptosis of human melanoma A375 cells via inhibition of the STAT3 signaling pathway. New J. Chem. 2023, 47, 120. <https://doi.org/10.1039/D2NJ04384J>
  • Xia Binbin, Li Yali, Liu Yang, Sun Wenfang, Chen Jing, Li Liushui, Pang Jingyao, Liu Xianjun, Chen Shicai, Cheng Hua, Alahmad Waleed: Rapid Separation of Asiatic Acid, Quercetin, and Kaempferol from Traditional Chinese Medicine Centella asiatica (L.) Urban Using HSCCC-Semi-Prep-HPLC and the Assessment of Their Potential as Fatty Acid Synthase Inhibitors. International Journal of Analytical Chemistry 2023, 2023, 1. <https://doi.org/10.1155/2023/7769368>
  • Chen Ya-Hui, Wu Jyun-Xue, Yang Shun-Fa, Hsiao Yi-Hsuan: Synergistic Combination of Luteolin and Asiatic Acid on Cervical Cancer In Vitro and In Vivo. Cancers 2023, 15, 548. <https://doi.org/10.3390/cancers15020548>
Crossref Cited-by Linking logo