Fol. Biol. 2021, 67, 143-149

https://doi.org/10.14712/fb2021067040143

Metabolic Effects of a Hydrophobic Alginate Derivative and Tetrahydrolipstatin in Rats Fed a Diet Supplemented with Palm Fat and Cholesterol

Milan Marounek1,2, Z. Volek1,2, T. Taubner2, M. Czauderna3

1Department of Microbiology, Nutrition and Dietetics, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, Prague, Czech Republic
2Department of Nutrition Physiology and Animal Product Quality, Institute of Animal Science, Prague, Czech Republic
3The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jablonna, Poland

Received June 2021
Accepted October 2021

References

1. Ackroff, K., Sclafani, A. (1996) Effects of the lipase inhibitor Orlistat on intake and preference for dietary fat in rats. Am. J. Physiol. I 271, R48-R54.
2. Alemany, M., Remesar, X., Fernández-López, J. A. (2003) Drug strategies for the treatment of obesity. IDrugs 6, 566-572.
3. Cruz-Hernandez, C., Oliveira, M., Pescia, G. J., Moulin, J., Masserey-Elmelegy, I., Dionisi, F., Destaillats, F. (2010) Lipase inhibitor orlistat decreases incorporation of eicosapentaenoic and docosahexaenoic acids in rat tissues. Nutr. Res. 30, 134-140. <https://doi.org/10.1016/j.nutres.2009.12.001>
4. Davis, R. A., Hyde, P. M., Kuan, J. C. W., Malonemcneal, M., Archambaultschexnayder, J. (1983) Bile acid secretion by cultured rat hepatocytes – regulation by cholesterol availability. J. Biol. Chem. 258, 3661-3667. <https://doi.org/10.1016/S0021-9258(18)32716-9>
5. Edashige, Y., Murakami, N., Tsujita, T. (2008) Inhibitory effect of pectin from the segment membrane of citrus fruits on lipase activity. J. Nutr. Sci. Vitaminol. 54, 409-415. <https://doi.org/10.3177/jnsv.54.409>
6. Guerciolini, R. (1997) Mode of action of orlistat. Int. J. Obesity 21, S12-S23.
7. Kobayashi, N., Noel, E. A., Barnes, A., Rosenberg, J., DiRusso, C., Black, P., Oyler, G. A. (2013) Rapid detection and quantification of triacylglycerol by HPLC-ELSD in Chlamydomonas reinhardtii and Chlorella strains. Lipids 48, 1035-1049. <https://doi.org/10.1007/s11745-013-3828-9>
8. Lee, Y. H., Jin, B., Lee, S. H., Song, M., Bae, H., Min, B. J., Park, J., Lee, D., Kim, H. (2016) Herbal formula HT048 attenuates diet-induced obesity by improving hepatic lipid metabolism and insulin resistance in obese rats. Molecules 21, 1424. <https://doi.org/10.3390/molecules21111424>
9. Lindsay, H. (1973) A colorimetric estimation of reducing sugars in potatoes with 3,5-dinitrosalicylic acid. Potato Res. 16, 176-179. <https://doi.org/10.1007/BF02356048>
10. Lu, J., Yang, H., Hao, J., Wu, C. L., Liu, L., Xu, N. Y., Linhardt, R. J., Zhang, Z. Q. (2015) Impact of hydrolysis conditions on the detection of mannuronic to guluronic ratio in alginate and its derivatives. Carbohyd. Polym. 122, 180-188. <https://doi.org/10.1016/j.carbpol.2015.01.008>
11. Mahmoud, R. H., Elnour, W. A. (2013) Comparative evaluation of the efficacy of ginger and orlistat on obesity management, pancreatic lipase and liver peroxisomal catalase enzyme in male albino rats. Eur. Rev. Med. Pharmacol. Sci. 17, 75-83.
12. Marounek, M., Volek, Z., Synytsya, A., Čopíková, J. (2007) Effect of pectin and amidated pectin on cholesterol homeostasis and cecal metabolism in rats fed a high-cholesterol diet. Physiol. Res. 56, 433-442. <https://doi.org/10.33549/physiolres.930967>
13. Marounek, M., Volek, Z., Dušková, D., Tůma, J., Taubner, T. (2013) Dose-response efficacy and long-term effect of the hypocholesterolemic effect of octadecylpectinamide in rats. Carbohydr. Polym. 97, 772-775. <https://doi.org/10.1016/j.carbpol.2013.05.044>
14. Marounek, M., Volek Z., Skřivanová E., Taubner, T., Pebriansyah, A., Dušková, D. (2017) Comparative study of the hypocholesterolemic and hypolipidemic activity of alginate and amidated alginate in rats. Int. J. Biol. Macromol. 105, 620-624. <https://doi.org/10.1016/j.ijbiomac.2017.07.077>
15. Marounek, M., Volek, Z., Taubner, T., Dušková, D., Čermák. L. (2019) Effect of amidated alginate on faecal lipids, serum and hepatic cholesterol in rats fed diets supplemented with fat and cholesterol. Int. J. Biol. Macromol. 122, 499-502. <https://doi.org/10.1016/j.ijbiomac.2018.10.180>
16. Melia, A. T., Koss-Twardy, S. G., Zhi, J. G. (1996) The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers. J. Clin. Pharmacol. 36, 647-653. <https://doi.org/10.1002/j.1552-4604.1996.tb04230.x>
17. Mortensen, A., Aguilar, F., Crebelli, R., Di Domenico, A., Dosemund, B., Frutos, M. J., Galtier, P., Gott, D., Gundert- Remy, U., Lambre, C., Leblanc, J. C., Lindtner, O., Moldeus, P., Mosesso, P., Oskarsson, A., Parent-Massin, D., Stankovic, I., Waalkens-Berendsen, I., Wright, M., Younes, M., Tobback, P., Ioannidou, S., Tasiopoulou, S., Woutersen, R. A. (2017) Re-evaluation of pectin (E440i) and amidated pectin (ET440ii) as food additives. EFSA Journal 15, 4866.
18. Porsgaard, T., Straarup, E. M., Mu, H. L., Høy, C. E. (2003) Effect of orlistat on fat absorption in rats: a comparison of normal rats and rats with diverted bile and pancreatic juice. Lipids 38, 1039-1043. <https://doi.org/10.1007/s11745-006-1158-x>
19. Sánchez-Machado, D. I., López-Cervantes, J., López-Hernández, J., Paseiro-Losada, P., Simal-Lozano, J. (2004) Determination of the uronic acid composition of seaweed dietary fibre by HPLC. Biomed. Chromatogr. 18, 90-97. <https://doi.org/10.1002/bmc.297>
20. Skřivan, M., Marounek, M., Engelmaierová, M., Čermák, L., Vlčková, J., Skřivanová, E. (2018) Effect of dietary fat type on intestinal digestibility of fatty acids, fatty acid profiles of breast meat and abdominal fat, and mRNA expression of lipid-related genes in broiler chickens. PLoS One 13, e0196035. <https://doi.org/10.1371/journal.pone.0196035>
21. Spielman, J., Stangl, G. I., Eder, K. (2008) Dietary pea protein stimulates bile acid excretion and lowers hepatic cholesterol concentration in rats. J. Anim. Physiol. Anim. Nutr. (Berl) 92, 683-693. <https://doi.org/10.1111/j.1439-0396.2007.00766.x>
22. Taubner, T., Marounek, M., Synytsya, A. (2017) Preparation and characterisation of amidated derivatives of alginic acid. Int. J. Biol. Macromol. 103, 202-207. <https://doi.org/10.1016/j.ijbiomac.2017.05.070>
23. Taubner, T., Marounek, M., Synytsya, A. (2020) Preparation and characterization of hydrophobic and hydrophilic amidated derivatives of carboxymethyl chitosan and carboxymethyl beta-glucan. Int. J. Biol. Macromol. 163, 1433-1443. <https://doi.org/10.1016/j.ijbiomac.2020.07.257>
24. Tsujita, T., Sumiyoshi, M., Han, L.-K., Fujiwara, T., Tsujita, J., Okuda, H. (2003) Inhibition of lipase activities by citrus pectin. J. Nutr. Sci. Vitaminol. (Tokyo) 49, 340-345. <https://doi.org/10.3177/jnsv.49.340>
25. Tůma, J., Volek, Z., Synytsya, A., Dušková, D., Marounek, M. (2014) Hydrophobically modified celluloses as novel cholesterol- lowering polymers. BioRes. 9, 4266-4273. <https://doi.org/10.15376/biores.9.3.4266-4273>
26. Wang, Q. C., Zhao, X., Pu, J. H., Luan, X. H. (2016) Influences of acidic reaction and hydrolytic conditions on monosaccharide composition analysis of acidic, neutral and basic polysaccharides. Carbohydr. Polym. 143, 296-300. <https://doi.org/10.1016/j.carbpol.2016.02.023>
27. Wilcox, M. D., Brownlee, I. A., Richardson, J. C. Dettmar, P. W., Pearson, J. P. (2014) The modulation of pancreatic lipase activity by alginates. Food Chem. 146, 479-484. <https://doi.org/10.1016/j.foodchem.2013.09.075>
28. Wu, J., Zhao, X., Ren, L., Xue, Y. T., Li, C. X., Xu, G. L., Guan, H. S. (2014) Determination of M/G ratio of propylene glycol alginate sodium sulfate by HPLC with pre-column derivatization. Carbohydr. Polym. 104, 23-28. <https://doi.org/10.1016/j.carbpol.2014.01.011>
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive