Fol. Biol. 2022, 68, 125-132

https://doi.org/10.14712/fb2022068040125

Antigen Presentation and Proteome Study of Exosomes Secreted by Co-Culture of Macrophages and Talaromyces marneffei

Zhi Xie, L. L. Li, G. J. Wei, C. Wang, D. H. Zhang, L. Wei

Department of Dermatology and Venereology, People’s Hospital of Guangxi Zhuang Autonomous Region, Guangxi 530000, China

Received October 2022
Accepted November 2022

References

1. Akira, S., Takeda, K., Kaisho, T. (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2, 675. <https://doi.org/10.1038/90609>
2. Bhatnagar, S., Shinagawa, K., Castellino, F. J., Schorey, J. S. (2007) Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo. Blood 110, 3234-3244. <https://doi.org/10.1182/blood-2007-03-079152>
3. Candiano, G., Bruschi, M., Musante, L., Santucci, L., Ghiggeri, G. M., Carnemolla, B. Orecchia, P., Zardi, L., Righetti, P. G. (2004) Blue silver: a very sensitive colloidal Coomassie G‐250 staining for proteome analysis. Electrophoresis 25, 1327-1333. <https://doi.org/10.1002/elps.200305844>
4. Denzer, K., Kleijmeer, M. J., Heijnen, H. F., Stoorvogel, W., Geuze, H. J. (2000) Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 113, 3365-3374. <https://doi.org/10.1242/jcs.113.19.3365>
5. Greening, D. W., Gopal, S. K., Xu, R., Simpson, R. J., Chen, W. (2015) Exosomes and their roles in immune regulation and cancer. Semin. Cell Dev. Biol. 40, 72-81. <https://doi.org/10.1016/j.semcdb.2015.02.009>
6. Hassani, K., Olivier, M. (2013) Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. PLoS Negl. Trop. Dis. 7, e2185. <https://doi.org/10.1371/journal.pntd.0002185>
7. Lu, S., Hu, Y., Lu, C., Zhang, J., Li, X., Xi, L. (2013) Development of in vitro macrophage system to evaluate phagocytosis and intracellular fate of Penicillium marneffei conidia. Mycopathologia 176, 11-22. <https://doi.org/10.1007/s11046-013-9650-3>
8. Mignot, G., Roux, S., Thery, C., Ségura, E., Zitvogel, L. (2006) Prospects for exosomes in immunotherapy of cancer. J. Cell. Mol. Med. 10, 376-388. <https://doi.org/10.1111/j.1582-4934.2006.tb00406.x>
9. Raimondo, F., Morosi, L., Chinello, C., Magni, F., Pitto, M. (2011) Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery. Proteomics 11, 709-720. <https://doi.org/10.1002/pmic.201000422>
10. Roilides, E., Lyman, C. A., Sein, T., Petraitiene, R., Walsh, T. J. (2003) Macrophage colony-stimulating factor enhances phagocytosis and oxidative burst of mononuclear phagocytes against Penicillium marneffei conidia. FEMS Immunol. Med. Microbiol. 36, 19-26. <https://doi.org/10.1016/S0928-8244(03)00035-X>
11. Shinobu, S., Fujikado, N., Furuta, T., Soo-hyun Chung, S. -H., Kotaki, H., Seki, K., Sudo, K., Akira, S., Adachi, Y., Ohno, N., Kinjo, T., Nakamura, K., Kawakami, K., Iwakura, I. (2007) Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat. Immunol. 8, 39.
12. Schnare, M., Barton, G. M., Holt, A. C., Takeda, K., Akira, S., Medzhitov, R. (2001) Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2, 947. <https://doi.org/10.1038/ni712>
13. Singh, P. P., Smith, V. L., Karakousis, P. C., Schorey, J. S. (2012) Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo. J. Immunol. 189, 777-785. <https://doi.org/10.4049/jimmunol.1103638>
14. Théry, C., Boussac, M., Véron, P., Ricciardi-Castagnoli, P., Raposo, G., Garin, J., Amigorena, S. (2001) Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J. Immunol. 166, 7309-7318. <https://doi.org/10.4049/jimmunol.166.12.7309>
15. van der Graaf, C. A. A., Netea, M. G., Verschueren, I., van der Meer, J. V. M. B., Kullberg, B. J. (2005) Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae. Infect. Immun. 73, 7458-7464. <https://doi.org/10.1128/IAI.73.11.7458-7464.2005>
16. Viriyakosol, S., Fierer, J., Brown, G. D., Kirkland, T. N. (2005) Innate immunity to the pathogenic fungus Cocci­dioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect. Immun. 73, 1553-1560. <https://doi.org/10.1128/IAI.73.3.1553-1560.2005>
17. Wang, J., Chen, C., Xie, P., Pan, Y., Tan, Y., Tang, L. (2013) Changes of cytokines and protein expression of macrophages stimulated with exosome from macrophages by Mycobacterium avium infection. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29, 123-126. (in Chinese)
front cover

ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

Open access journal

Submissions

Archive