Folia Biologica
Journal of Cellular and Molecular Biology, Charles University 

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Fol. Biol. 2026, 72, 59-67

https://doi.org/10.14712/fb2026.0006

Wip1 Inhibition Enhances the Therapeutic Efficacy of Palbociclib in Luminal A Breast Cancer by Modulating Cell Cycle Progression and Apoptosis

Gökhan Çolak1ID, Nazllcan Kaygusuz2,3ID, Nezih Meydan1,4ID, Esin Oktay1ID, Mehtap Kılıc Eren2,5ID

1Faculty of Medicine, Department of Medical Oncology, Aydin Adnan Menderes University, Aydin, Türkiye
2Faculty of Medicine, Department of Medical Biology, Aydin Adnan Menderes University, Aydin, Türkiye
3Izmir Biomedicine and Genome Center, Dokuz Eylul University, Izmir, Türkiye
4Department of Medical Oncology, Medicana International Hospital University, Istanbul, Türkiye
5ADU-BILTEM, Aydin Adnan Menderes University, Aydin, Türkiye

Received August 3, 2025
Accepted January 29, 2026

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ISSN 0015-5500 (Print) ISSN 2533-7602 (Online)

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