Fol. Biol. 2017, 63, 35-41
Putative Effects of Sex Hormones on Urinary Tract Infection
Urinary tract infections affect mostly females. The infection and possible consequent ascent of bacteria is enhanced by various risk factors. Sex hormones regulate gene transcription implicated in immune cell development and maturation, in regulation of immune responses and immune signalling pathways. Limited knowledge is available; however, recent findings underline the importance of understanding the interactions between sex hormones and urinary tract infection to diminish the occurrence of complications related to this infection. This review summarizes and discusses the current knowledge on the correlation and impact of sex hormones on urinary tract infections.
Keywords
kidney disease, bacteriuria, bladder, oestrogen, testosterone, progesterone.
Funding
This work was funded by Slovak Ministry of Education, Science, Research and Sport – grant number VEGA 1/0222/14.
References
Copyright
This is an open-access article distributed under the terms of the Creative Commons Attribution License.