Fol. Biol. 2017, 63, 35-41

https://doi.org/10.14712/fb2017063020035

Putative Effects of Sex Hormones on Urinary Tract Infection

Tereza Brachtlová, Roman Gardlík, Ľubomíra Tóthová

Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia

Received December 2015
Accepted January 2017

Urinary tract infections affect mostly females. The infection and possible consequent ascent of bacteria is enhanced by various risk factors. Sex hormones regulate gene transcription implicated in immune cell development and maturation, in regulation of immune responses and immune signalling pathways. Limited knowledge is available; however, recent findings underline the importance of understanding the interactions between sex hormones and urinary tract infection to diminish the occurrence of complications related to this infection. This review summarizes and discusses the current knowledge on the correlation and impact of sex hormones on urinary tract infections.

Funding

This work was funded by Slovak Ministry of Education, Science, Research and Sport – grant number VEGA 1/0222/14.

References

53 live references